BML-210

HDAC inhibitor

Catalog No. SIH-348

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CAS No. 537034-17-6
Molecular Formula C20H25N3O2
SKU: SIH-348 Categories: ,

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SIH-348_BML-210_Chemical_Structure.png
Product Name BML-210
Description

HDAC inhibitor

Purity >98% (TLC); NMR (Conforms)
CAS No. 537034-17-6
Molecular Formula C20H25N3O2
Molecular Weight 339.4
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble in 25 mg/ml DMSO or 10 mg/ml Ethanol
Source Synthetic
Appearance Tan Solid
SMILES C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NC2=CC=CC=C2N
InChI InChI=1S/C20H25N3O2/c21-17-12-8-9-13-18(17)23-20(25)15-7-2-1-6-14-19(24)22-16-10-4-3-5-11-16/h3-5,8-13H,1-2,6-7,14-15,21H2,(H,22,24)(H,23,25)
InChIKey RFLHBLWLFUFFDZ-UHFFFAOYSA-N
Safety Phrases Classification: Caution- Substance not yet fully tested.
Safety Phrases:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Hazard Statements:
H413 – May cause long lasting harmful effects to aquatic life.
Cite This Product Bml-210 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-348)

Biological Description

Alternative Names N1-(2-aminophenyl)-N8-phenyloctanediamide
Research Areas Cancer, Cell Signaling
PubChem ID 9543540
Scientific Background A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 µM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines.
References 1. Savickiene J., et al. (2006) Eur. J. Pharmacol. 549: 9.
2. Herman D., et al. (2006) Nature Chem. Biol. 10: 551.

Product Images

<p>Chemical structure of BML-210 (SIH-348), a HDAC inhibitor. CAS #: 537034-17-6. Molecular Formula: C20H25N3O2 . Molecular Weight: 339.4 g/mol.</p>

Chemical structure of BML-210 (SIH-348), a HDAC inhibitor. CAS #: 537034-17-6. Molecular Formula: C20H25N3O2 . Molecular Weight: 339.4 g/mol.

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