Difluoromethylornithine

ODC Inhibitor

Catalog No. SIH-200

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CAS No. 70052-12-9
Molecular Formula C6H12F2N2O2•HCl
SKU: SIH-200 Categories: ,

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SIH-200_Difluoromethylornithine_Chemical_Structure.png
Product Name Difluoromethylornithine
Description

ODC Inhibitor

Purity >98%
CAS No. 70052-12-9
Molecular Formula C6H12F2N2O2•HCl
Molecular Weight 218.63
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble to 75 mM in water
Source Synthetic
Appearance White Solid
SMILES FC(F)NC(CCCN)C(O)=O
InChI InChI=1S/C6H12F2N2O2/c7-6(8)10-4(5(11)12)2-1-3-9/h4,6,10H,1-3,9H2,(H,11,12)/t4-/m0/s1
InChIKey LDLGBNXSBZFATB-BYPYZUCNSA-N
Safety Phrases Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Cite This Product Difluoromethylornithine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-200)

Biological Description

Alternative Names N2-(Difluoromethyl)ornithine, DFMO, Eflornithine
Research Areas Apoptosis, Cancer
PubChem ID 3009
Scientific Background Inhibitor of ornithine decarboxylase that inhibits polyamine biosynthesis. Displays anti-apoptotic, anti-angiogenic and anti-parasitic activity.
References 1. Malhotra B., Noveck R., Behr D., Palmisano M. (2001) J Clin Pharmacol. 41: 972-978.

Product Images

<p>Chemical structure of Difluoromethylornithine (SIH-200), a Inhibits polyamine biosynthesis. CAS #: 70052-12-9. Molecular Formula: C6H12F2N2O2 * HCl. Molecular Weight: 218.63 g/mol.</p>

Chemical structure of Difluoromethylornithine (SIH-200), a Inhibits polyamine biosynthesis. CAS #: 70052-12-9. Molecular Formula: C6H12F2N2O2 * HCl. Molecular Weight: 218.63 g/mol.

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