Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: PK-11195
Catalog #: SIH-224-5MG
Size: 5mg
Type: Inducer
Description: Mitochondrial benzodiazepine receptor ligand
Research Area: Apoptosis
CAS Number: 85532-75-8
Formula: C21H21CIN2O
Molecular weight: 352.86
Source/Host: Synthetic
Purity: >98%
Solubility: Soluble to 75mM in ethanol and to 100mM in DMSO.
Appearance: White crystals
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed
R68- Possible risk of irreversible effects
Datasheet: SIH 224 PK 11195 Apoptosis Inducer
Price: $51.00 USD Add to Cart Bulk Quote

Structure of PK-11195

Research Background: PK-11195 is an isoquinoline carboxamide which binds selectively to the peripheral benzodiazepine receptor (PBR). It has a high affinity for the PBR in all species (1). It has also been successfully used in PET scans to visualize brain inflammation in patients with neuronal damage (2).
References: 1. Pike V.W., et al. (1993) Nucl Med & Bio. 20(4): 503-525.
2. Buck J.R., et al. (2011) J Nucl Med. 52(1): 107-114.

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