Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: N,N-Dimethylsphingosine
Catalog #: SIH-235-25MG
Size: 25mg
Type: Inducer
Description: Inhibits sphingosine kinase
Research Area: Apoptosis
CAS Number: 119567-63-4
Formula: C20H41NO2
Molecular weight: 327.6
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble in DMSO (25mg/mL) or 100% ethanol (25mg/mL).
Appearance: White to off white waxy solid, or viscous oil
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Risk Phrases: R20/21/22- Harmful by inhalation, in contact with skin and if swallowed
Datasheet: SIH 235 N,N Dimethylsphingosine Apoptosis Inducer
Price: $239.00 USD Add to Cart Bulk Quote

Structure of N,N-Dimethylsphingosine

Research Background: N,N-dimethylsphingosine is a potent and specific inhibitor of sphingosine kinase. It is a natural metabolite of sphiongosine in some cancel cell lines and tissues (1). It also induces apoptosis, but it is not an inhibitor of protein kinase C (2).
References: 1. Yatomi Y., et al. (1996) Biochem. 35: 626-633.
2. Sweeny E.A., et al. (1996) Int J Cancer. 66(3): 358- 366.

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