Small Molecules - Apoptosis, Cellular Oxidative Stress,

Home > Products > Small Molecules > SIH-246-50MG

Product Name: Mitomycin C
Catalog #: SIH-246-50MG
Alternative Names: Ametycine
Size: 50mg
Type: Inducer
Description: DNA crosslinking and damaging agent
Research Area: Apoptosis
CAS Number: 50-07-7
Formula: C15H18N4O5
Molecular weight: 334.33
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 100mM in DMSO, 5mM water, and to 5mM Ethanol.
Appearance: Dark Purple Crystalline Solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Very toxic. May be fatal if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)

Risk Phrases: R26/27/28 - Very Toxic by inhalation, in contact with skin and if swallowed
R46 - May cause heritable genetic damage
R61 - May cause harm to the unborn child
R62 - Possible risk of impaired fertility

Hazard Phrases: H302-H351

Precautionary Phrases: P281
Datasheet: SIH 246 Mitomycin C Apoptosis Inducer
Price: $399.00 USD Add to Cart Bulk Quote

Structure of Mitomycin C

Research Background: The mitomycins are a family of aziridine containing natural products. Mitomycin C is a chemotherapeutic agent because of its mechanism of potent DNA crosslinker, reductive activation followed by two N-alklyations. Both alkylations are sequence specific for a guanine nucleoside in the sequence 5’-CpG-3’ (1).
References: 1. Tomasz M. (1995). Chem and Biol. 2(9): 575-579.

Full Name:	*
Company:	*
Phone:	*
Email:	*
Address:	*
Address 2:
City:	*
State/Province:
Country:	*
Zip/Postal:	*
Primary Work Interest:	*
Newsletter Sign-Up:	* Yes No
Check box before sending form:	*