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Product Name: SKF-96365
Catalog #: SIH-305-25MG
Size: 25mg
Type: Inhibitor
Description: TRPC channel blocker
Research Area: Ion Channels
CAS Number: 130495-35-1
Formula: C22H26N2O3 HCl
Molecular weight: 402.92
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 100mM in water.
Appearance: White solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Irritant. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Hazard Phrases: H315-H319-H335

Precautionary Phrases: P261-P305 + P351 + P338
Datasheet: SIH 305 SKF 96365 HCl Ion Channel Inhibitor
Price: $329.00 USD Add to Cart Bulk Quote

Structure of SKF-96365

Research Background: SKF-96365 is a selective inhibitor of receptor mediated Ca2+ entry and voltage-gated Ca2+ entry (1). It has also been shown o inhibit cytochrome P-450 mediated reactions (1,2), and reversibly activates non-selective cation channels in human endotherlial cells (1,3).
References: 1. Leis H.J., et al. (1995) Br J Pharmacol. 114(3): 598-601.
2. Sheets J.J., Mason J.I., Wise C.A. and Eastabrook R.W. (1986) Biochem Pharmacol. 35: 487-491.
3. Schwarz G., Droogmans G. and Nilius B. (1994) Cell Calcium. 15: 45-54.

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