Ionomycin

Ca2+ ionophore

Catalog No. SIH-228

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CAS No. 56092-81-0
Molecular Forumla C41H70O9

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Overview

Product Name Ionomycin
Description

Ca2+ ionophore

Purity >98%
CAS No. 56092-81-0
Molecular Formula C41H70O9
Molecular Weight 709.01

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inducer
Solubility Soluble to 10 mM in ethanol and to 10 mM in DMSO
Source Synthetic
Appearance Colorless Solid
SMILES C[[email protected]](CCC(=O)O)C[[email protected]](C)C[[email protected]](C)C(=O)/C=C(/[[email protected]](C)C[[email protected]](C)C/C=C/[C@@H](C)[[email protected]]([C@@H](C)[[email protected]](C[C@@H]1CC[C@@](O1)(C)[[email protected]]2CC[C@@](O2)(C)[C@@H](C)O)O)O)O
InChI InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23
InChIKey PGHMRUGBZOYCAA-OJFQOPKISA-N
Safety Phrases Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H302
Cite This Product Ionomycin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-228)

Biological Description

Alternative Names (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-22-{(2S,2'R,5S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptamethyl-9-oxo-10,16-docosadi enoic acid, Ionomycin calcium salt
Research Areas Cancer, Apoptosis
PubChem ID 6434517
Scientific Background Ionomycin is a calcium ionophore used in research to raise the intracellular level of calcium and as a tool to understand calcium transport across biological membranes. It is also used to stimulare the intracellular production of the cytokines interferon, perforin, IL-2 and IL-4. It is more specific than A23187.
References 1. Holmes A.G. Watt M.J., Carey A.L. And Febbraio M.A. (2004) Metabolism. 53(11): 1492-1495.
2. Abramov A.Y., Duchen M.R. (2003) Cell Calcium. 33(2): 101-112.

Product Images

Chemical structure of Ionomycin (SIH-228), a Ca2+ ionophore. CAS #: 56092-81-0. Molecular Formula: C41H70O9. Molecular Weight: 709.01 g/mol.

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