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| Product Name | Quisqualic Acid |
| Description |
Glutamate receptor agonist |
| Purity | 99.2% |
| CAS No. | 52809-07-1 |
| Molecular Formula | C5H7N3O5 |
| Molecular Weight | 189.13 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Agonist |
| Solubility | Soluble to 100 mM in 1eq. NaOH; 10 mM in water |
| Source | Isolated from Quisqualis fructus |
| Appearance | Off white solid |
| SMILES | [C@H](N)(CN1OC(=O)NC1=O)C(=O)O |
| InChI | InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1 |
| InChIKey | ASNFTDCKZKHJSW-REOHCLBHSA-N |
| Safety Phrases |
Classification: Not WHMIS controlled. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H302 + H312 Harmful if swallowed or in contact with skin H332 Harmful if inhaled. Precautionary statements: P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ protective clothing. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. P322 Specific measures (see supplemental first aid instructions on this label). P330 Rinse mouth. P363 Wash contaminated clothing before reuse. P501 Dispose of contents/ container to an approved waste disposal plant. |
| Cite This Product | Quisqualic Acid (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-418) |
Biological Description
| Alternative Names | (L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid |
| Research Areas | AMPA Receptors, Glutamate Receptors, Ion Channels, Neuroscience, Neurotransmitter Receptors |
| PubChem ID | 40539 |
| Scientific Background | Quisqualic acid is a glutamate receptor and AMPA ionotropic receptors agonist. It is also known to sensitize neurons in hippocampus to depolarization by L-AP6. |
| References |
1. Schulte M., Roon R., Chalmers D., Sunter D., & Koerner J. (1994) Brain Res. 203-7. 2. Schoepp D., & Conn P. (1993) Trends Pharmacol Sci. 13-20. |
Product Images
Chemical structure of Quisqualic Acid (SIH-418), a Glutamate receptor agonist. CAS #: 52809-07-1. Molecular Formula: C5H7N3O5. Molecular Weight: 189.13 g/mol.
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