Zafirlukast

Hsp70 inhibitor

Catalog No. SIH-361

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CAS No. 107753-78-6
Molecular Forumla C31H33N3O6S

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Overview

Product Name Zafirlukast
Description

Hsp70 inhibitor

Purity >98% (TLC); NMR (Conforms)
CAS No. 107753-78-6
Molecular Formula C31H33N3O6S
Molecular Weight 575.7

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble in 25 mg/ml DMSO
Source Synthetic
Appearance White to Pink Solid
SMILES CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(C=C2)CC3=CN(C4=C3C=C(C=C4)NC(=O)OC5CCCC5)C)OC
InChI InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32
InChIKey YEEZWCHGZNKEEK-UHFFFAOYSA-N
Safety Phrases Classification: Caution- Substance not yet fully tested.
Safety Phrases:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Cite This Product Zafirlukast (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-361)

Biological Description

Alternative Names Cyclopentyl [3-(2-methoxy-4-{[(2-methylphenyl)sulfonyl]carbamoyl}benzyl)-1-methyl-1H-indol-5-yl]carbamate; ICI-204219
Research Areas Cancer, Heat Shock
PubChem ID 5717148
Scientific Background HSP70 inhibitor ( IC50=37 µM). Leukotriene antagonist. Clinically useful antiasthmatic agent. Cell permeable. Looking for more information on HSP70? Visit our new HSP70 Scientific Resource Guide at http://www.HSP70.com.
References 1. Miyata Y., et al. (2010) J. Biomol. 15: 1211.

Product Images

Chemical structure of Zafirlukast (SIH-361), a Hsp70 inhibitor. CAS #: 107753-78-6. Molecular Formula: C31H33N3O6S . Molecular Weight: 575.7 g/mol.

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