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Phosphorylation

Phosphorylation is defined as the introduction of a phosphate group into an organic molecule. Phosphorylation has many functions including being an important regulator, activation of molecules, inhibiting protein activity, turning a nonpolar hydrophobic protein into a polar hydrophilic molecule and causing the binding of proteins to activate or inhibit particular cell signaling systems. Concomitantly, the process of de-phosphorylation (the removal of a phosphate group) plays a reciprocal and important role in the regulation of these functions too.

Phospho-specific antibodies are a powerful tool because of their ability to detect protein phosphorylation at very specific sites. This can lead to a highly specific analysis of what is occurring in the cell or cellular pathway under given experimental conditions. They are therefore critical reagents both for basic research and for clinical diagnosis.


Product Catalog # Size Type Description Price More Info
p38α MAPKinase, 9F12 SMC-152C 25 µg Antibodies Monoclonal Contact Local Distributor more...
p38α MAPKinase, 9F12 SMC-152D 100 µg Antibodies Monoclonal Contact Local Distributor more...
p70 S6K Antibody SPC-146F 400 µL Antibodies Polyclonal Contact Local Distributor more...
p90 RSK1 Antibody SPC-147F 400 µL Antibodies Polyclonal Contact Local Distributor more...
Phosphoserine Antibody SPC-149F 400 µL Phospho & Chemical State Specific Antibodies / Antibodies Polyclonal Contact Local Distributor more...
Phosphoserine Antibody: HRP Conjugate SPC-151F 400 µL Phospho & Chemical State Specific Antibodies / Antibodies Polyclonal Contact Local Distributor more...
Phosphothreonine Antibody SPC-154F 400 µL Phospho & Chemical State Specific Antibodies / Antibodies Polyclonal Contact Local Distributor more...
Phosphothreonine Antibody: HRP SPC-152F 400 µL Phospho & Chemical State Specific Antibodies / Antibodies Polyclonal Contact Local Distributor more...
Phosphotyrosine Antibody SPC-161F 400 µL Phospho & Chemical State Specific Antibodies / Antibodies Polyclonal Contact Local Distributor more...
Phosphotyrosine Antibody: Biotin Conjugate SPC-163F 400 µL Phospho & Chemical State Specific Antibodies / Antibodies Polyclonal Contact Local Distributor more...
Phosphotyrosine Antibody: HRP Conjugate SPC-162F 400 µL Phospho & Chemical State Specific Antibodies / Antibodies Polyclonal Contact Local Distributor more...
PKB beta (Akt2) Antibody SPC-148F 400 µL Antibodies Polyclonal Contact Local Distributor more...