Phosphorylation
Phosphorylation is defined as the introduction of a phosphate group into an organic molecule. Phosphorylation has many functions including being an important regulator, activation of molecules, inhibiting protein activity, turning a nonpolar hydrophobic protein into a polar hydrophilic molecule and causing the binding of proteins to activate or inhibit particular cell signaling systems. Concomitantly, the process of de-phosphorylation (the removal of a phosphate group) plays a reciprocal and important role in the regulation of these functions too.
Phospho-specific antibodies are a powerful tool because of their ability to detect protein phosphorylation at very specific sites. This can lead to a highly specific analysis of what is occurring in the cell or cellular pathway under given experimental conditions. They are therefore critical reagents both for basic research and for clinical diagnosis.
| Catalog # | Product | Size | Type | Price | More Info | |
| SMC-152C | p38α MAPKinase, 9F12 | 25 µg | Monoclonal | Contact Local Distributor 
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| SMC-152D | p38α MAPKinase, 9F12 | 100 µg | Monoclonal | Contact Local Distributor
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| SPC-146F | Anti p70 S6K Antibody | 400 µl | Polyclonal | Contact Local Distributor
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| SPC-147F | Anti p90 RSK1 Antibody | 400 µl | Polyclonal | Contact Local Distributor
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| SPC-148F | Anti PKB beta (Akt2) Antibody | 400 µl | Polyclonal | Contact Local Distributor
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| SPC-149F | Anti Phosphoserine Antibody | 400 µl | Polyclonal | Contact Local Distributor
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| SPC-151F | Anti Phosphoserine Antibody: HRP Conjugate | 400 µl | Polyclonal | Contact Local Distributor
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| SPC-152F | Anti Phosphothreonine Antibody: HRP | 400 µl | Polyclonal | Contact Local Distributor
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| SPC-154F | Anti Phosphothreonine Antibody | 400 µl | Polyclonal | Contact Local Distributor
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| SPC-161F | Anti Phosphotyrosine Antibody | 400 µl | Polyclonal | Contact Local Distributor
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| SPC-162F | Anti Phosphotyrosine Antibody: HRP Conjugate | 400 µl | Polyclonal | Contact Local Distributor
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| SPC-163F | Anti Phosphotyrosine Antibody: Biotin Conjugate | 400 µl | Polyclonal | Contact Local Distributor
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