Apoptosis

What is Apoptosis?

Apoptosis, or programmed cell death, is a tightly regulated process found in multicellular organisms that is required for normal development as well for maintaining homeostasis. If cells are no longer needed, they commit suicide by activating an intracellular death program. This signal can come from the cell itself, from the surrounding tissue, or from a cell that is part of the immune system.

Malfunction of this process is believed to coincide with the incidents of a number of human diseases, including neurodegenerative disorders and cancer. The apoptotic process (which differs significantly from necrosis) is characterized by a number of morphological and biochemical alterations including membrane blebbing, cell shrinkage, chromatin condensation and DNA fragmentation.

Apoptosis research requires a great diversity of life science products. We are dedicated to developing cutting edge research products to aid in the study of apoptosis, including monoclonal antibodies, polyclonal antibodies, antibody conjugates, proteins, immunoassays, and small molecule inhibitors.

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