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| Product Name | Baicalein |
| Description |
Lipoxygenase inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 491-67-8 |
| Molecular Formula | C15H10O5 |
| Molecular Weight | 270.2 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (15 mg/ml) |
| Source | Synthetic |
| Appearance | Yellow to Yellow-green Crystalline powder |
| SMILES | OC1=C(O)C(O)=C2C(=O)C=C(OC2=C1)C1=CC=CC=C1 |
| InChI | InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H |
| InChIKey | FXNFHKRTJBSTCS-UHFFFAOYSA-N |
| Safety Phrases | Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | Baicalein (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-579) |
Biological Description
| Alternative Names | 5,6,7-Trihydroxyflavone; 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one; Biacalein |
| Research Areas | Alzheimer's Disease, Apoptosis, Cancer, Cell Cycle, Neurodegeneration, Neuroscience |
| PubChem ID | 5281605 |
| Scientific Background | Baicalein is a flavonoid that is positive allosteric modulator of the GABA A Receptor (1). It also inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils (2). |
| References | 1. Zhang S.Q., et al. (2013) J Neurosci. Res. 91(9): 1239-1246. 2. Zhu M., et al. (2004) J Biol Chem. 279(26): 26846-26857. |
Product Images
Chemical structure of Baicalein (SIH-579), a Lipoxygenase inhibitor. CAS #: 491-67-8. Molecular Formula: C15H10O5. Molecular Weight: 270.24 g/mol.
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