Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Sphingosine
Catalog #: SIH-202-100MG
Size: 100mg
Type: Inhibitor
Description: Protein Kinase C inhibitor
Research Area: Apoptosis
CAS Number: 128-78-4
Formula: C18H37NO2
Molecular weight: 299.49
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 100mM in DMSO.
Appearance: Solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Datasheet: SIH 202 Sphingosine Apoptosis Inhibitor
Price: $265.00 USD Add to Cart Bulk Quote

Structure of Sphingosine

Research Background: Sphingosine can be phosphorylated in vivo via two kinases which leads to the formation of a potent signaling lipid. It is a selective inhibitor of protein kinase C, but does not inhibit protein kinase A or myosin light chain kinase. It also inhibits calmodulin-dependent enzymes and is the precursor of ceramide.
References: 1. Radin N. (2003) Biochem J. 371(Pt2): 243-256.
2. Carter H.E., Glick F.J., Norris W.P., Phillips G.E. (1947) J Biol Chem. 170: 285-295.

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