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| Product Name | TPCK |
| Description |
Serine protease inhibitor |
| Purity | >98% |
| CAS No. | 402-71-1 |
| Molecular Formula | C17H18CI3O3S |
| Molecular Weight | 351.85 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO (>10 mg/ml) and in 10 mM in methanol and ethanol (50 mg/ml) |
| Source | Synthetic |
| Appearance | White Solid |
| SMILES | ClCC(=O)C(NS(=O)(=O)c1ccc(cc1)C)Cc2ccccc2 |
| InChI | InChI=1S/C17H18ClNO3S/c1-13-7-9-15(10-8-13)23(21,22)19-16(17(20)12-18)11-14-5-3-2-4-6-14/h2-10,16,19H,11-12H2,1H3/t16-/m0/s1 |
| InChIKey | MQUQNUAYKLCRME-INIZCTEOSA-N |
| Safety Phrases |
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: 37/38-41 Hazard Phrases: H315-H318-H335 Precautionary Phrases: P261-P280-P305 + P351 + P338 |
| Cite This Product | TPCK (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-207) |
Biological Description
| Alternative Names | N-(4-Chloro-3-oxo-1-phenyl-2-butanyl)-4-methylbenzenesulfonamide |
| Research Areas | Apoptosis, Cancer |
| PubChem ID | 9824 |
| Scientific Background | Tosyl phenylalanyl chloromethyl ketone is a protease inhibitor. It also inhibits some cysteine proteases (1). |
| References | 1. Farrelll S.O., Campbell M.K. (2006) Biochemistry. Australia: Thomson Brooks/Cole. P.160. |
Product Images
Chemical structure of TPCK (SIH-207), a Serine protease inhibitor. CAS #: 402-71-1. Molecular Formula: C17H18CI3O3S. Molecular Weight: 351.85 g/mol.
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