Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Forskolin
Catalog #: SIH-208-50MG
Size: 50mg
Type: Inhibitor
Description: Adenylate cyclase activator
Research Area: Apoptosis
CAS Number: 66575-29-9
Formula: C22H34O7
Molecular weight: 410.51
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 100mM in DMSO, and to 10mM in ethanol.
Appearance: White Solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Caution: Substance not yet fully tested.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Hazard Phrases: H312

Precautionary Phrases: P280
Datasheet: SIH 208 Forskolin Apoptosis Inhibitor
Price: $459.00 USD Add to Cart Bulk Quote

Structure of Forskolin

Research Background: Forskolin resensitizes cell receptors by activating adenyl cyclase, and increasing the intracellular levels of cAMP (1). Medically forskolin provides a route to inhibition of colon cancer cell growth and survival (2). It is also a vasodilator, may be helpful in controlling the cause of glaucoma (3), reduces urinary tract infections, and may help to increase the skin’s natural resistance to burning under UV light (1).
References: 1. Passeron T., Namiki T., Passeron H.J., Le Pape E., and Hearing V.J. (2009) J Invest Dermatol. 129(1): 162-166.
2. McEwan D.G., Brunton V.G., Baillie G.S., Leslie N.R., Houslay M.D., and Frame M.C. (2007) Cancer Research. 67(11).
3. Pescosolido N., and Librando A. (2010) Clin Ter. 161(3): e81-5.

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