Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Amifostine
Catalog #: SIH-210-50MG
Size: 50mg
Type: Inhibitor
Description: Cellular protectant
Research Area: Apoptosis
CAS Number: 20537-88-6
Formula: C5H15N2O3PS
Molecular weight: 214.22
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble in water
Appearance: White Solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Hazard Phrases: H302
Datasheet: SIH 210 Amifostine Apoptosis Inhibitor
Price: $239.00 USD Add to Cart Bulk Quote

Structure of Amifostine

Research Background: Amifostine is a cytoprotective adjuvant used in cancer chemotherapy and radiotherapy. Inside cells it detoxifies reactive metabolites of platinum and alkylating agents (1, 2). Other effects include accelerated DNA repair (1), induction of cellular hypoxia (1), inhibition of apoptosis (2), alteration of gene expression (2) and modification of enzyme activity (2).
References: 1. Kouvaris J.R., Kouloulias V.E., Blahos L.J. (2007) Oncologist. 12(6): 738-747.
2. Amifostine: BC Cancer Agency. 2006-03-01.

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