Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Mifepristone (RU486)
Catalog #: SIH-211-500MG
Alternative Names: RU486, RU 38487
Size: 500mg
Type: Inhibitor
Description: Glucocorticoid antagonist
Research Area: Apoptosis
CAS Number: 84371-65-3
Formula: C29H35NO2
Molecular weight: 429.6
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 100mM in DMSO, and to 50mM in ethanol.
Appearance: Yellow solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Risk Phrases: R60- May impair fertility
R61- May cause harm to the unborn child

Hazard Phrases: H360

Precautionary Phrases: P201-P308 + P313
Datasheet: SIH 211 Mifepristone Apoptosis Inhibitor
Price: $219.00 USD Add to Cart Bulk Quote

Structure of Mifepristone

Research Background: Mifepristone is a progesterone receptor antagonist used as an abortifacient. It is also an antiglucocorticoid and an antiandrogen. Its relative binding affinity at the progesterone receptor is twice that of progesterone, its affinity at the glucocorticoid receptor is 3x that of dexamethasone, and more than 10 times that of cortisol (1).
References: 1. Heikinheim O., Kekkonen R. and Lahteenmaki P. (2003) Contraception. 68(6): 421-426.

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