Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Brefeldin A
Catalog #: SIH-225-50MG
Size: 50mg
Type: Inducer
Description: Inhibits intracellular transport
Research Area: Apoptosis
CAS Number: 20350-15-6
Formula: C16H24O4
Molecular weight: 280.36
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 10mM in ethanol and to 50mM in DMSO.
Appearance: White Crystalline Solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Risk Phrases: R68- Possible risk of irreversible effects

Hazard Phrases: H301

Precautionary Phrases: P301 + P310
Datasheet: SIH 225 Brefeldin A Apoptosis Inducer
Price: $345.00 USD Add to Cart Bulk Quote

Structure of Brefeldin A

Research Background: Brefeldin A is a reversible inhibitor of proteins from the endoplasmic reticulum (ER) to the golgi. In mammalian and yeast cells, Brefeldin A targets certain GTP-exchange factosr responsible for activating a GTPase called Arf1p (1, 2).
References: 1. Klausner R.D., Donaldson J.G., Lippincott-Schwartz J. (1992) J Cell Biol. 116(5): 1071-1080.
2. Nebenfuhr A., Ritzenthaler C., and Robinson D.G. (2002) Plant Physiol. 130(3): 1102-1108.

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