Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Puromycin
Catalog #: SIH-248-250MG
Size: 250mg
Type: Inducer
Description: Translation inhibitor
Research Area: Apoptosis
CAS Number: 58-58-2
Formula: C22H29N7O5 x 2HCl
Molecular weight: 544.43
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 100M in water and 100mM in DMSO.
Appearance: White Solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Datasheet: SIH 248 Puromycin Apoptosis Inducer
Price: $175.00 USD Add to Cart Bulk Quote

Structure of Puromycin

Research Background: Puromycin is an antibiotic that is a protein synthesis inhibitor that causes premature chain termination during translation taking place in the ribosome. Part of the molecule resembles the 3’ end of the tRNA. It enters the A site and transfers to the growing chain, causing the premature release. It is not selective for either prokaryotes or eukaryotes.
References: 1. Azzam and Algranati. (1973) Proc Natl Acad Sci. 70: 3866.

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