LY 294002

PI 3-Kinase inhibitor

Catalog No. SIH-252

5 out of 5 based on 1 customer rating
CAS No. 154447-36-6
Molecular Formula C19H17NO3•HCl
SKU: SIH-252 Categories: ,

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SIH-252_LY_294002_Chemical_Structure.png
Product Name LY 294002
Description

PI 3-Kinase inhibitor

Purity >98%
CAS No. 154447-36-6
Molecular Formula C19H17NO3•HCl
Molecular Weight 343.81
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble to 5 mM in ethanol and to 25 mM in DMSO
Source Synthetic
Appearance White Crystalline Solid
SMILES C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4
InChI InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
InChIKey CZQHHVNHHHRRDU-UHFFFAOYSA-N
Safety Phrases Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Cite This Product LY 294002 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-252)

Biological Description

Alternative Names 2-(4-Morpholinyl)-8-phenyl-4H-chromen-4-one
Research Areas Apoptosis, Cancer, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors
PubChem ID 3973
Scientific Background LY294002 is a potent inhibitor of PI3Ks. It inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo (1).
References 1.  Vlahos, et al. (1994) J Biol Chem. 269: 5241.

Product Images

<p>Chemical structure of LY 294002 (SIH-252), a PI 3-Kinase inhibitor. CAS #: 154447-36-6. Molecular Formula: C19H17NO3 * HCl. Molecular Weight: 343.81 g/mol.</p>

Chemical structure of LY 294002 (SIH-252), a PI 3-Kinase inhibitor. CAS #: 154447-36-6. Molecular Formula: C19H17NO3 * HCl. Molecular Weight: 343.81 g/mol.

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