Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: CAPE
Catalog #: SIH-263-250MG
Alternative Names: caffeic acid phenethyl ester
Size: 250mg
Type: Inducer
Description: Inhibits NFkB activation
Research Area: Apoptosis
CAS Number: 104594-70-9
Formula: C17H16O4
Molecular weight: 284.31
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 100mM in DMSO, acetone, ethanol, methanol, acetonitrile.
Appearance: Off-white solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Caution: Substance not yet fully tested.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Hazard Phrases: H315-H319-H335

Precautionary Phrases: P261-P305 + P351 + P338
Datasheet: SIH 263 Caffeic acid phenethyl ester (CAPE) Apoptosis Inducer
Price: $229.00 USD Add to Cart Bulk Quote

Structure of CAPE

Research Background: CAPE , an active component of propolis from honeybee hives is known to have antioxidant, antimitogenic, anticarcinogenic, anti-inflammatory and antiviral properties (1). It specifically inhibits NF-κB activation and inhibits the growth of transformed cells (1). Also suppresses lipid peroxidation and inhibits ornithine decarboxylase, protein tyrosine kinase and lipoxygenase activities.
References: 1. Natarajan K., Singh S., Burke T.R., Grunberger D., Aggarwal B.B. (1996) Proc Natl Acad Sci USA. 93(17): 9090-9095.

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