Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Resveratrol
Catalog #: SIH-264-500MG
Size: 500mg
Type: Inducer
Description: Antioxidant
Research Area: Apoptosis
CAS Number: 501-36-0
Formula: C14H12O3
Molecular weight: 228.25
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 100mM in DMSO, 100mM in ethanol.
Appearance: Off-white solid
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Caution: Substance not yet fully tested.

Safety Phrases: S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Hazard Phrases: H302-H315-H317-H318-H335

Precautionary Phrases: P261-P280-P305 + P351 + P338
Datasheet: SIH 264 Resveratrol Apoptosis Inducer
Price: $185.00 USD Add to Cart Bulk Quote

Structure of Resveratrol

Research Background: Resveratrol is a stilbenoid and a phytoalexin produced naturally by several plants. Its effects are numerous and include anti-cancer (1), anti-inflammatory (2), anti-fungal and has other beneficial cardiovascular effects. It has been proposed that Mn SOD is increased by the pathwayRESV-SIRT1/Nad+- FOXO3a- MnSOD (3). In terms of its anti-cancer properties, resveratrol modulates the transcription factor NF-KB and inhibition of the cytochrome P450 enzyme (1, 4).
References: 1. Leiro J., et al. (2005) Int Immunopharm. 5(2): 393-406.
2. Gentilli M, et al. (2001) Life Sciences. 68(11): 1317-1321.
3. Robb E.L., et al. (2008) Biochem Biophys Res Commun. 367(2): 406-412.
4. Chun Y.J., Kim M.Y., Guengerich F.P. (1999) Biochem Biophys Res Commun. 262(1): 20-24.

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