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Product Name: Capsaicin
Catalog #: SIH-322-1G
Size: 1g
Type: Inhibitor
Description: TRPV1opener
Research Area: Ion Channels
CAS Number: 404-86-4
Formula: (CH3)2CHCH=CH(CH2)4CONHCH2C6H3-4-(OH)-3-(OCH3)
Molecular weight: 305.41
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble in 100% ethanol, methanol or chloroform. Sparingly soluble in water.
Appearance: Off-white solid
Storage Temp: 4°C
Shipping Temp: Blue Ice or 4°C
Safety Phrases: Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.

Safety Phrases: S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes

Risk Phrases: 25-37/38-41-42/43

Hazard Phrases: H301-H311-H315-H317-H318-H334-H335

Precautionary Phrases: P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
Datasheet: SIH 322 Capsaicin Ion Channel Inhibitor
Price: $339.00 USD Add to Cart Bulk Quote

Structure of Capsaicin

Research Background: Capsaicin is an agonist at the TRPV1 receptor, a ligand-gated non-selective cation channel (1, 2). It exhibits neuroprotective effects in a model of transient global cerebral ischemia and induces release of substance P from afferent nociceptive specific neurons (1). Powerful excitant of peripheral sensory nerve endings, specifically unmyelinated afferent neurons (C-fibers). Reversibly inhibits aggregation of platelets (3).
References: 1. Caterina M.J., et al. (1997) Nature. 389(6653): 816-824.
2. Story G.M., Crus-Orengo L. (2007) Am Scientist. 95(4): 326-333.
3. Vaishnava P., Wang D.H. (2003) Curr Med Chem Cadiovasc Hematol Agents. 1(2): 177-188.

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