SMER3

Name: SMER3
SKU: SIH-341
Availability: InStock

E3 UB ligase inhibitor

Catalog No. SIH-341

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CAS No.	67200-34-4
Molecular Formula	C11H4N4O2

SKU: SIH-341 Categories: Inhibitor, Small Molecules

Product Name	SMER3
Description	E3 UB ligase inhibitor
Purity	>98%
CAS No.	67200-34-4
Molecular Formula	C₁₁H₄N₄O₂
Molecular Weight	224.18
Field of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Storage Temperature	-20ºC
Shipping Temperature	Shipped Ambient
Product Type	Inhibitor
Solubility	Soluble in 75 mM DMSO
Source	Synthetic
Appearance	Yellow Solid
SMILES	C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O
InChI	InChI=1S/C11H4N4O2/c16-9-6-4-2-1-3-5(6)7-8(9)13-11-10(12-7)14-17-15-11/h1-4H
InChIKey	SFSSAKVWCKFRHE-UHFFFAOYSA-N
Safety Phrases	Classification: Caution – Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes
Cite This Product	SMER3 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-341)

Alternative Names	9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Research Areas	Apoptosis, Cancer
PubChem ID	568763
Scientific Background	Specific inhibitor of a yeast SCF family E3 ubiquitin ligase (SCF) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation. Enhancer of rapamycin.
References	1. Aghajanyy et al. (2010) Nat.Biotechnol. 28: 738.

Chemical structure of SMER3 (SIH-341), a E3 UB ligase inhibitor. CAS #: 67200-34-4. Molecular Formula: C11H4N4O2. Molecular Weight: 224.18 g/mol.

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