PJ-34

Name: PJ-34
SKU: SIH-366
Availability: InStock

PARP inhibitor

Catalog No. SIH-366

0 out of 5 based on 0 customer ratings

Reviews (0) | Datasheet

CAS No.	344458-15-7
Molecular Formula	C17H17N3O2•HCL•H2O

SKU: SIH-366 Categories: Inhibitor, Small Molecules

Product Name	PJ-34
Description	PARP inhibitor
Purity	>98% (HPLC); NMR (conforms)
CAS No.	344458-15-7
Molecular Formula	C₁₇H₁₇N₃O₂•HCL•H₂O
Molecular Weight	331.8
Field of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Storage Temperature	-20ºC
Shipping Temperature	Shipped Ambient
Product Type	Inhibitor
Solubility	May be dissolved in DMSO (30 mg/ml) or water (20 mg/ml)
Source	Synthetic
Appearance	White to yellow solid.
SMILES	CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl
InChI	InChI=1S/C17H17N3O2/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22)
InChIKey	UYJZZVDLGDDTCL-UHFFFAOYSA-N
Safety Phrases	Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Cite This Product	PJ-34 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-366)

Alternative Names	N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,Ndimethylacetamide . HCl
Research Areas	Apoptosis, Cancer, Cancer Growth Inhibitors, PARP Inhibitors
PubChem ID	4858
Scientific Background	PJ-34 is a selective inhibitor of Poly (ADP-Ribose) polymerase (PARP). Studies have shown that the use of PJ-34 on severe inflammatory diseases, in particular experimental allergic encephalomyelitis (EAE) have contributed to a shift of the immune response from a pro-inflammatory Th1 to anti-inflammatory th2 phenotype (1).
References	1. Scott G., Kean R., Mikheeva., Fabis M., Mabley J.J. (2004) The Journal of Pharmacology and Exp. Therapeutics. 310(3): 1053-1061.

Chemical structure of PJ-34 (SIH-366), a PARP inhibitor. CAS #: 344458-15-7. Molecular Formula: C17H17N3O2 *HCL * H2O. Molecular Weight: 331.8 g/mol.

There are no reviews yet.

Be the first to review “PJ-34”