Kainic acid

Kainate agonist

Catalog No. SIH-364

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CAS No. 58002-62-3
Molecular Forumla C10H15NO4•H2O

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Overview

Product Name Kainic acid
Description

Kainate agonist

Purity >99% (HPLC)
CAS No. 58002-62-3
Molecular Formula C10H15NO4•H2O
Molecular Weight 213.2

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Agonist
Solubility May be dissolved in water (10 mg/ml)
Source Synthetic
Appearance White powder
SMILES CC(=C)[[email protected]]1CN[C@@H]([[email protected]]1CC(=O)O)C(=O)O
InChI InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
InChIKey VLSMHEGGTFMBBZ-OOZYFLPDSA-N
Safety Phrases Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Cite This Product Kainic acid (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-364)

Biological Description

Alternative Names (2S,3S,4S)-3-(carboxymethyl)-4-(prop-1-en-2-yl)-pyrrolidine-2-carboxylic acid, Monohydrate
Research Areas Glutamate Receptors, Ion Channels, Kainate Receptors, Neuroscience, Neurotransmitter Receptors
PubChem ID 10255
Scientific Background Kainic acid is a conformationally restricted glutamate analog which acts as a selective agonist at kainate receptors. It is a central nervous system stimulant and neurotoxin. It acts as a classic neuroexcitatory agent for induction of seizures in laboratory animals (typical dose 10-30 mg/kg).
References 1. Watkins J.C., et al. (1981) Ann. Rev. Pharmacol. Toxicol. 21: 165.

Product Images

Chemical structure of Kainic acid (SIH-364), a Neuro-excitant/ Kainate agonist. CAS #: 58002-62-3. Molecular Formula: C10H15NO4 (*H2O). Molecular Weight: 213.2 g/mol.

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