Triacsin C

Acyl-CoA synthetase inhibitor

Catalog No. SIH-203

5.00 out of 5 based on 1 customer rating
CAS No. 76896-80-5
Molecular Forumla C11H17N3O
Rated 5.00 out of 5 based on 1 customer rating
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Product Name Triacsin C
Description

Acyl-CoA synthetase inhibitor

Purity >98%
CAS No. 76896-80-5
Molecular Formula C11H17N3O
Molecular Weight 207.27

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble in DMSO (25 mg/ml) or methanol (5 mg/ml)
Source Synthetic
Appearance Oil dissolved in DMSO (1mg/ml)
SMILES CCC/C=C/C/C=C/C=C/C=N/NN=O
InChI InChI=1S/C11H17N3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h4-5,7-11H,2-3,6H2,1H3,(H,13,15)/b5-4+,8-7+,10-9+,12-11+
InChIKey NKTGCVUIESDXPU-YLEPRARLSA-N
Safety Phrases Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Cite This Product Triacsin C (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-203)

Biological Description

Alternative Names (3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane
Research Areas Cancer, Apoptosis
PubChem ID 9576787
Scientific Background Triacsin C is a potent inhibitor of long fatty acyl CoA synthetase. It blocks beta-cell apoptosis. It also blocks the de novo synthesis of triglyercides, diglycerides and cholesterol esters, interfering with lipid metabolism (1). It is also a potent vasodilator.
References 1.  Igal R.A., Wang P., Coleman R.A. (1997) Biochem J. 324(Pt2): 529-534.

Product Images

<p>Chemical structure of Triacsin C (SIH-203), a Fatty acyl-CoA synthase inhibitor. CAS #: 76896-80-5. Molecular Formula: C11H17N3O . Molecular Weight: 207.27 g/mol.</p>

Chemical structure of Triacsin C (SIH-203), a Fatty acyl-CoA synthase inhibitor. CAS #: 76896-80-5. Molecular Formula: C11H17N3O . Molecular Weight: 207.27 g/mol.

Product Citations (1)

Other Citations

Eicosapentaenoic Acid Prevents Saturated Fatty Acid-Induced Vascular Endothelial Dysfunction: Involvement of Long-Chain Acyl-CoA Synthetase.

Ishida, T. et al. (2015) J Atheroscler Thromb. 22(11):1172-85.

PubMed ID: 26016511 Applications: In vitro inhibition

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