Product Citations for Neurodegenerative Proteins
StressMarq’s proteins for neurodegenerative disease research (monomers, pre-formed fibrils and oligomers) have been cited in many peer-reviewed scientific journals. Here is a chronological list of product citations for StressMarq’s alpha synuclein, tau, and amyloid beta. To see a complete list of all citations for a product, please refer to the product-specific webpage.
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Alpha Synuclein Citations
[Newest – Oldest]
- Facile generation of drug-like conformational antibodies specific for amyloid fibrils. Desai, A.A. et al. Nat Chem Biol. May 2025.
- Catalog# SPR-317: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2)
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Catalog# SPR-332: Human Recombinant N-Terminal Acetylated Alpha Synuclein Pre-formed Fibrils (Type 1)
- Catalog# SPR-484: Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable)
- Astrocytes carrying LRRK2 G2019S exhibit increased levels of clusterin chaperone via miR-22-5p and reduced ability to take up α-synuclein fibrils. Filippini, A. et al. Acta Neuropathol Commun. May 2025.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Retinoid X receptor as a therapeutic target to treat neurological disorders associated with α-synucleinopathy. Zhylkibayev, A. et al. Cells. May 2025.
- Catalog# SPR-321: Human Recombinant Alpha Synuclein Monomers (Type 1)
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Alpha-synuclein misfolding as fluid biomarker for Parkinson’s disease measured with the iRS platform. Schuler, M. et al. EMBO Mol Med. Apr 2025.
- Catalog# SPR-321: Human Recombinant Alpha Synuclein Monomers (Type 1)
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Catalog# SPR-466: Human Recombinant Alpha Synuclein Oligomers (Dopamine HCl Stabilized)
Co-aggregation of AF594 and AF488-labelled Alpha Synuclein A90C Mutant Monomers (catalog# SPR-478). In-depth method previously described by Horrocks et al. (2015).
- Trehalose-releasing nanogels reduce α-synuclein-induced Lewy body-like inclusions in primary mouse hippocampal neurons. Maruf, A. et al. J Mater Chem B. Apr 2025.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Astrocytic RNA editing regulates the host immune response to alpha-synuclein. D’Sa, K. et al. Sci Adv. Apr 2025.
- Catalog# SPR-321: Human Recombinant Alpha Synuclein Monomers (Type 1)
- Peptidomimetics activating the proteasome: A new perspective for Parkinson’s treatment. Trepczyk, K. et al. J Med Chem. Apr 2025.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- A single-molecule liposome assay for membrane permeabilisation. Bąk, K.M. et al. Angew Chem Int Ed Engl. Apr 2025.
- Catalog# SPR-478: Human Recombinant Alpha Synuclein A90C Mutant Monomers
- Leucine-rich repeat kinase 2 promotes disintegration of retinal pigment epithelial cell: Implication in the pathogenesis of dry age-related macular degeneration. Suimon, Y. et al. Am J Pathol [Preproof]. Apr 2025.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Myeloid FtH regulates macrophage response to kidney injury by modulating Snca and ferroptosis. Chatterjee, T. et al. bioRxiv [Preprint]. Mar 2025.
Immunohistochemistry analysis of Female Sprague-Dawley Rat brain injected with Human Alpha Synuclein Pre-formed Fibrils (Type 1) (catalog# SPR-322).
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Catalog# SPR-517-A488: Human Recombinant Alpha Synuclein E114C Mutant Monomers: ATTO 488
- A 3D gut-brain-vascular platform for bidirectional crosstalk in gut-neuropathogenesis. Cho, H. et al. Research Square [Preprint]. Mar 2025.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Targeting the ClpP-αSynuclein interaction with a decoy peptide to mitigate neuropathology in Parkinson’s disease models. Hu, D. et al. bioRxiv [Preprint]. Feb 2025.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Glucosylceramide induced ectosomes propagate pathogenic α-synuclein in Parkinson’s disease. Jacquemyn, J. et al. bioRxiv [Preprint]. Feb 2025.
- Catalog# SPR-322-A594: Human Recombinant Alpha Synuclein Pre-formed Fibrils: ATTO 594 (Type 1)
- Cholesterol-mediated lysosomal dysfunction in APOE4 astrocytes promotes α-synuclein pathology in human brain tissue. Mesentier-Louro, L. A. et al. bioRxiv [Preprint]. Feb 2025.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)

UV-CD data comparing StressMarq’s Alpha Synuclein Type 1 (catalog# SPR-322) and Type 2 (catalog# SPR-317) PFFs. Both have a high beta sheet/turn content, with small secondary structure differences.
- 14-3-3θ phosphorylation exacerbates alpha-synuclein aggregation and toxicity. Wang, B. et al. Neurobiol Dis [Preproof]. Jan 2025.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Parkinson disease-associated toxic exposures selectively upregulate vesicular glutamate transporter vGlut2 in a model of human cortical neurons. Clark, K. A. et al. Mol Biol Cell. Jan 2025.
- Catalog# SPR-316: Human Recombinant Alpha Synuclein Monomers (Type 2)
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- From literature identification to efficient validation of targets – effects on alpha-synuclein aggregation in cortical neurons. Orrhult, L.S. et al. Cellectricon [Sweden]. Nov 2024.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- High-molecular-weight oligomer tau (HMWoTau) species are dramatically increased in Braak-stage dependent manner in the frontal lobe of human brains, demonstrated by a novel oligomer Tau ELISA with a mouse monoclonal antibody (APNmAb005). Fukumoto, H. et al. FASEB J. Nov 2024.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Catalog# SPR-484: Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable)
- Exploring the potential of biomimetic peptides in targeting fibrillar and filamentous alpha-synuclein — An in silico and experimental approach to Parkinson’s disease. Frantzeskos, S. A. et al. Biomimetics. Nov 2024.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- STAT3 inhibitor increases α-synuclein in PFF-treated astroglia cells by dysregulating autophagy and potentially affects exosome biogenesis. Luo, Y. et al. Neuromolecular Med. Oct 2024.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
Thioflavin T seeding assay. Alpha Synuclein Pre-formed Fibrils (Type 1) conjugated to ATTO 594 (catalog# SPR-322-A594) show similar seeding capabilities as unconjugated Alpha Synuclein PFFs (catalog# SPR-322).
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- A brain-shuttled antibody targeting alpha synuclein aggregates for the treatment of synucleinopathies. An, S. et al. bioRxiv [Preprint]. Oct 2024.
- Catalog# SPR-321: Human Recombinant Alpha Synuclein Monomers (Type 1)
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Catalog# SPR-322-A594: Human Recombinant Alpha Synuclein Pre-formed Fibrils: ATTO 594 (Type 1)
- Catalog# SPR-326: Human Recombinant A53T Mutant Alpha Synuclein Pre-formed Fibrils (Type 1)
- PDCD4 triggers α-synuclein accumulation and motor deficits via co-suppressing TFE3 and TFEB translation in a model of Parkinson’s disease. Cao, B. et al. NPJ Parkinsons Dis. Aug 2024.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Low-density lipoprotein receptor-related protein 1 mediates α-synuclein transmission from the striatum to the substantia nigra in animal models of Parkinson’s disease. Luo, H. et al. Neural Regen Res. July 2024.
- Catalog# SPR-321: Human Recombinant Alpha Synuclein Monomers (Type 1)
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Gut microbiota produces biofilm-associated amyloids with potential for neurodegeneration. Fernández-Calvet, A. et al. Nature Communications. May 2024.
- Catalog# SPR-321: Human Recombinant Alpha Synuclein Monomers (Type 1)
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)

StressMarq’s Human Alpha Synuclein Pre-formed Fibrils (Type 1) (red), catalog# SPR-322, were shown to be taken up by SH-SY5Y cells and transmitted to neuronal iPSCs within 14 days. Blue: Hoechst/DNA; Green: SHSY5Y-GFP; Red: SPR-322; Purple: Tubulin.
- Identification of glycerol 3-phosphate acyltransferase as a potent modifier of α-synuclein-induced toxicity. Lim, K.L. et al. Research Square [Preprint]. Apr 2024.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Catalog# SPR-323: Mouse Recombinant Alpha Synuclein Monomers (Type 1)
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy. Parmasad, J.L. et al. Cell Death Dis. Mar 2024.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- FABP2 is involved in intestinal α-synuclein pathologies. Sekimori, T. et al. J Integr Neurosci. Feb 2024.
- Catalog# SPR-322-A594: Human Recombinant Alpha Synuclein Pre-formed Fibrils: ATTO 594 (Type 1)
- C-terminally truncation is a prominent post-translational modification of human erythrocyte α-synuclein. Amagai, R. et al. J Biochem. Feb 2024.
- Catalog# SPR-331: Human Recombinant N-Terminal Acetylated Alpha Synuclein Monomers (Type 1)
- Immunization effects of a novel α-synuclein-based peptide epitope vaccine in Parkinson’s disease-associated pathology. Park, J. S. et al. Vaccines. Dec 2023.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Fluorescent peptide-based probe for the detection of alpha-synuclein aggregates in the gut. Sim, R. et al. bioRxiv [Preprint]. Nov 2023.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
Immunohistochemistry analysis of rat brain injected with Mouse Alpha Synuclein Pre-formed Fibrils (Type 1) (catalog# SPR-324). Species: Female Sprague-Dawley Rat. Alpha synuclein pathology is seen in the periform/insular cortex and the cingulate cortex on both the same (ipsi) and opposite (contra) sides as the injection sites.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Two-color coincidence single-molecule pulldown for the specific detection of disease-associated protein aggregates. Saleeb, R.S. et al. Sci Adv. Nov 2023.
- Catalog# SPR-321: Human Recombinant Alpha Synuclein Monomers (Type 1)
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Catalog# SPR-484: Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable)
- α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity. Horvath, J.D. et al. Cell Rep. Oct 2023.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- A novel NOX inhibitor alleviates Parkinson’s disease pathology in PFF-injected mice. Ofori, K. et al. Int J Mol Sci. Sept 2023.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Mutant α-synuclein propagates via the lymphatic system of the brain in the monomeric state. Fujita, K. et al. Cell Rep. Aug 2023.
- Catalog# SPR-325: Human Recombinant A53T Mutant Alpha Synuclein Monomers (Type 1)
- Targeted degradation of α-synuclein aggregates in Parkinson’s disease using the AUTOTAC technology. Lee, J. et al. Mol Neurodegener. Jun 2023.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease. Nim, S. et al. Nat Commun. Apr 2023.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
TEM of Human Alpha Synuclein Oligomers (Kinetically-Stable) (catalog# SPR-484).
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Aggregation of alpha-synuclein in enteric neurons does not impact function in vitro. Bindas, A.J. et al. Sci Rep. Dec 2022.
- Catalog# SPR-322-A594: Human Recombinant Alpha Synuclein Pre-formed Fibrils: ATTO 594 (Type 1)
- Granulovacuolar degeneration bodies are independently induced by tau and α-synuclein pathology. Jorge-Oliva, M. et al. Alzheimers Res Ther. Dec 2022.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Observation of α-synuclein preformed fibrils interacting with SH-SY5Y neuroblastoma cell membranes using scanning ion conductance microscopy. Feng, C. et al. ACS Chem Neurosci. Dec 2022.
- Catalog# SPR-317: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2)
- Reelin protects against pathological α-synuclein accumulation and dopaminergic neurodegeneration after environmental enrichment in Parkinson’s disease. Cho, E. et al. Neurobiol Dis. Dec 2022.
- Catalog# SPR-326: Human Recombinant A53T Mutant Alpha Synuclein Pre-formed Fibrils (Type 1)
- LRP1 is a neuronal receptor for α-synuclein uptake and spread. Chen, K. et al. Mol Neurodegener. Sept 2022
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Catalog# SPR-484: Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable)
- Rational generation of monoclonal antibodies selective for pathogenic forms of alpha-synuclein. Gibbs, E. et al. Biomedicines. Sept 2022.
Thioflavin T seeding assay. Mouse Alpha Synuclein Pre-formed Fibrils (Type 1) (catalog# SPR-324) seed the formation of new alpha synuclein fibrils from the pool of Mouse Alpha Synuclein Monomers (Type 1) (catalog#SPR-323).
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- A novel NOX inhibitor treatment attenuates Parkinson’s disease-related pathology in mouse models. Ghosh, A.A. Int J Mol Sci. Apr 2022.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Cell culture media, unlike the presence of insulin, affect α-synuclein aggregation in dopaminergic neurons. Hlushchuk, I. et al. Biomolecules. Apr 2022.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Design, synthesis and chemically engineered graphene quantum dot applications: contrast agent for MR imaging and targeted therapeutics on Parkinson’s treatment. Poonkuzhali, K. et al. SSRN. Mar 2022.
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Heat shock protein 70 as a sex-skewed regulator of α-synucleinopathy. Bhatia, T.N. et al. Neurotherapeutics. Oct 2021
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Alpha-synuclein preformed fibrils induce cellular senescence in Parkinson’s disease models. Verma, D.K. et al. Cells. Jul 2021.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
TEM of A53T alpha synuclein Pre-formed fibrils (catalog# SPR-326).
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Domain-independent inhibition of CBP/p300 attentuates α-synuclein aggregation. Hlushchuk, I. et al. ACS Chem Neurosci. Jul 2021.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Reelin alleviates mesenchymal stem cell senescence and reduces pathological α-synuclein expression in an in vitro model of Parkinson’s disease. Cho, E. et al. Genes (Basel). Jul 2021.
- Catalog# SPR-326: Human Recombinant A53T Mutant Alpha Synuclein Pre-formed Fibrils (Type 1)
- Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones. Yakubu, U.M et al. J Biol Chem. Mar 2021.
- Catalog# SPR-321: Human Recombinant Alpha Synuclein Monomers (Type 1)
- Catalog# SPR-322: Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
- The SUMO conjugase Ubc9 protects dopaminergic cells from cytotoxicity and enhances the stability of α-synuclein in Parkinson’s disease models. Verma, D.K. et al. eNeuro. Sept 2020.
- Catalog# SPR-324: Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)
Tau Citations
[Newest – Oldest]
- Facile generation of drug-like conformational antibodies specific for amyloid fibrils. Desai, A.A. et al. Nat Chem Biol. May 2025.
- Catalog# SPR-329: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils
- Catalog# SPR-330: Human Recombinant Tau (K18) P301L Mutant Pre-formed Fibrils
- Catalog# SPR-475: Mouse Recombinant Tau-430 (2N4R) P290S Mutant Pre-formed Fibrils (Human P301S Equivalent)
- Catalog# SPR-491: Human Recombinant Tau-352 (fetal 0N3R) Wild-Type Pre-formed Fibrils
- Detection of misfolded proteins in neurodegenerative disease models with a highly sensitive chemiluminescence probe. Zhu, B. et al. bioRxiv [Preprint]. Apr 2025.
- Catalog# SPR-330: Human Recombinant Tau (K18) P301L Mutant Pre-formed Fibrils
- Macropinocytosis of aggregated amyloid-beta and tau requires Arf6 and the RhoGTPases Rac1, Cdc42 and RhoA. Krupa, J. et al. bioRxiv [Preprint]. Mar 2025.
TEM of Human Recombinant Tau-441 (2N4R) P301S Mutant Protein Filaments (catalog# SPR-463).
- Catalog# SPR-329-A488: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils: ATTO 488
- Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency. Kasen, A. et al. bioRxiv [Preprint]. Mar 2025.
- Catalog# SPR-463: Human Recombinant Tau-441 (2N4R) P301S Mutant Filaments
- Catalog# SPR-480: Human Recombinant Tau-441 (2N4R) Wild-Type Pre-formed Fibrils
- Temperature-dependent aggregation of tau protein is attenuated by native PLGA nanoparticles under in vitro conditions. Sil Paul, P. et al. Int J Nanomedicine. Feb 2025.
- Catalog# SPR-480: Human Recombinant Tau-441 (2N4R) Wild-Type Pre-formed Fibrils
- A novel IncRNA FAM151B-DT regulates autophagy and degradation of aggregation prone proteins. Renganathan, A. et al. medRxiv [Preprint]. Jan 2025.
- Catalog# SPR-480: Human Recombinant Tau-441 (2N4R) Wild-Type Pre-formed Fibrils
- Reversal of neuronal tau pathology via adiponectin receptor activation. McGregor, E. R. et al. Commun Biol. Jan 2025.
- Catalog# SPR-329: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils
- Parkinson disease-associated toxic exposures selectively upregulate vesicular glutamate transporter vGlut2 in a model of human cortical neurons. Clark, K. A. et al. Mol Biol Cell. Jan 2025.
Thioflavin T seeding assay. Tau-441 (2N4R) P301S Mutant PFFs (catalog# SPR-329) seed the formation of new tau fibrils from the pool of corresponding monomers (catalog# SPR-327).
- Catalog# SPR-480: Human Recombinant Tau-441 (2N4R) Wild-Type Pre-formed Fibrils
- Microglia internalize tau monomers and fibrils using distinct receptors but similar mechanisms. Falkon, K. F. et al. Alzheimers Dement. Dec 2024.
- Catalog# SPR-327: Human Recombinant Tau-441 (2N4R) P301S Mutant Monomers
- Catalog# SPR-329: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils
- Thonningianin A from Penthorum chinense Pursh as a targeted inhibitor of Alzheimer’s disease-related β-amyloid and Tau proteins. Yu, L. et al. Phytother Res. Sept 2024.
- Catalog# SPR-330: Human Recombinant Tau (K18) P301L Mutant Pre-formed Fibrils
- FGFR3 drives Aβ-induced tau uptake. Kim, D. et al. Exp Mol Med. July 2024.
- Catalog# SPR-330: Human Recombinant Tau (K18) P301L Mutant Pre-formed Fibrils
- Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy. Toral-Rios, D. et al. J Exp Med. Apr 2024.
- Catalog# SPR-329-A488: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils: ATTO 488
- Catalog# SPR-471: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils (Baculovirus/Sf9)
- BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1. Lin, H. et al. Autophagy. Mar 2024.
TEM of Human Recombinant Tau-441 (2N4R), Wild-Type Pre-formed Fibrils (catalog# SPR-480).
- Catalog# SPR-480: Human Recombinant Tau-441 (2N4R) Wild-Type Pre-formed Fibrils
- Reduced proganulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase. Takahashi, H. et al. Nat Commun. Feb 2024.
- Catalog# SPR-327: Human Recombinant Tau-441 (2N4R) P301S Mutant Monomers
- ApoE4 expression disrupts tau uptake, trafficking, and clearance in astrocytes. Eisenbaum, M. et al. Glia. Jan 2024.
- Catalog# SPR-329-A488: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils: ATTO 488
- Catalog# SPR-479: Human Recombinant Tau-441 (2N4R) Wild-Type Monomers
- Catalog# SPR-480: Human Recombinant Tau-441 (2N4R) Wild-Type Pre-formed Fibrils
- APOE3ch alters microglial spread and suppresses Aβ-induced seeding and spread. Chen, Y. et al. Cell. Jan 2024.
- Catalog# SPR-329: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils
- Complement receptor 4 mediates the clearance of extracellular tau fibrils by microglia. Yoo, C. et al. Research Square [Preprint]. Nov 2023.
- Catalog# SPR-327: Human Recombinant Tau-441 (2N4R) P301S Mutant Monomers
- Catalog# SPR-329: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils
- α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity. Horvath, J.D. et al. Cell Rep. Oct 2023.
- Catalog# SPR-480: Human Recombinant Tau-441 (2N4R) Wild-Type Pre-formed Fibrils
Immunohistochemistry analysis of P301L mouse hippocampus injected with Human Recombinant Tau (K18) P301L Mutant Pre-formed Fibrils (catalog# SPR-330).
- Catalog# SPR-480: Human Recombinant Tau-441 (2N4R) Wild-Type Pre-formed Fibrils
- A human neuron/astrocyte co-culture to model seeded and spontaneous intraneuronal tau aggregation. Batenburg, K.L. et al. Curr Protoc. Oct 2023.
- Catalog# SPR-330: Human Recombinant Tau (K18) P301L Mutant Pre-formed Fibrils
- In vivo near-infrared fluorescence imaging selective for soluble amyloid beta aggregates using y-shaped BODIPY derivative. Akasaka, T. et al. J Med Chem. Oct 2023.
- Catalog# SPR-477: Human Recombinant Tau (K18) Delta K280 Mutant Pre-formed Fibrils
- Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release. Adrian, M. et al. Nat Commun. Oct 2023.
- Catalog# SPR-471: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils (Baculovirus/Sf9)
- Catalog# SPR-479: Human Recombinant Tau-441 (2N4R) Wild-Type Monomers
- Increased G3BP2-tau interaction in tauopathies is a natural defense against tau aggregation.Wang, C. et al. Neuron. Sept 2023.
- Catalog# SPR-329-A488: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils: ATTO 488
- Catalog# SPR-471: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils (Baculovirus/Sf9)
- Quantitative flow cytometric selection of tau conformational antibodies specific for pathological aggregates. Zupancic, J.M. et al. Front Immunol. Aug 2023.
TEM of Human Recombinant Truncated Tau Fragment (AA297-391) (dGAE) Pre-formed Fibrils (catalog# SPR-461).
- Catalog# SPR-329: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils
- Catalog# SPR-461: Human Recombinant Truncated Tau Fragment (AA297-391) (dGAE) Pre-formed Fibrils
- Mutant β1-adrenergic receptor improves REM sleep and ameliorates tau accumulation in a mouse model of tauopathy. Dong, Q. et al. PNAS. Apr 2023.
- Catalog# SPR-329: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils
- A phosphoinositide signalling pathway mediates rapid lysosomal repair. Tan, J.X. & Finkel, T. Nature. Sept 2022.
- Catalog# SPR-329: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils
- Exosomal tau with seeding activity is released from Alzheimer’s disease synapses, and seeding potential is associated with amyloid beta. Miyoshi, E. et al. Lab Invest. Dec 2021.
- Catalog# SPR-475: Mouse Recombinant Tau-430 (2N4R) P290S Mutant Pre-formed Fibrils (Human P301S Equivalent)
- Astrocyte senescence and SASP in neurodegeneration: tau joins the loop. Ungerleider, K. et al. Cell Cycle. Apr 2021.
- Catalog# SPR-444: Human Recombinant Truncated Tau Fragment (AA297-391) (dGAE) Monomers
- Catalog# SPR-461: Human Recombinant Truncated Tau Fragment (AA297-391) (dGAE) Pre-formed Fibrils
- Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology. Sandusky-Beltran, L.A. et al. J Clin Invest. Feb 2021.
- Catalog# SPR-329: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils
- Cornel iridoid glycoside regulates modification of tau and alleviates synaptic abnormalities in aged P301S mice. Yang, C. et al. Curr Med Sci. Dec 2020.
- Catalog# SPR-327: Human Recombinant Tau-441 (2N4R) P301S Mutant Monomers
- Catalog# SPR-329: Human Recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils
Amyloid Beta Citations

AFM of Human Synthetic Amyloid Beta 1-42 Pre-formed Fibrils (catalog# SPR-487).
[Newest – Oldest]
- Advanced Alzheimer’s disease models using iPSC-derived microglia and neurons harboring disease-related gene variants. Shatri, E.B. et al. Bioneer [Denmark]. Apr 2025.
- Catalog# SPR-487: Human Synthetic Amyloid Beta 1-42 Pre-formed Fibrils
- Catalog# SPR-488: Human Synthetic Amyloid Beta 1-42 Oligomers
- Epitope sequence and modification fingerprints of anti-Aβ antibodies. Talucci, I. et al. bioRxiv [Preprint]. Mar 2025.
- Catalog# SPR-485: Human Synthetic Amyloid Beta 1-42 Peptide (HFIP-treated)
- Catalog# SPR-487: Human Synthetic Amyloid Beta 1-42 Pre-formed Fibrils
- Catalog# SPR-488: Human Synthetic Amyloid Beta 1-42 Oligomers
- The Alzheimer’s disease gene SORL1 regulates lysosome function in the human microglia. Mishra, S. et al. bioRxiv [Preprint]. Jan 2025.
- Catalog# SPR-488: Human Synthetic Amyloid Beta 1-42 Oligomers
- High-molecular-weight oligomer tau (HMWoTau) species are dramatically increased in Braak-stage dependent manner in the frontal lobe of human brains, demonstrated by a novel oligomer Tau ELISA with a mouse monoclonal antibody (APNmAb005). Fukumoto, H. et al. FASEB J. Nov 2024.
- Catalog# SPR-487: Human Synthetic Amyloid Beta 1-42 Pre-formed Fibrils
- Catalog# SPR-488: Human Synthetic Amyloid Beta 1-42 Oligomers
- Hybrid amyloid quantum dot nano-bio assemblies to probe neuroinflammatory damage. Chiang, W. et al. ACS Chem Neurosci. Aug 2024.
- Catalog# SPR-488: Human Synthetic Amyloid Beta 1-42 Oligomers
- Ultrasensitive detection of aggregated α-synuclein using quiescent seed amplification assay for the diagnosis of Parkinson’s disease. Mao, H. et al. Transl Neurodegener. Jul 2024.
- Catalog# SPR-487: Human Synthetic Amyloid Beta 1-42 Pre-formed Fibrils
- Chimeric antigen receptor macrophages target and resorb amyloid plaques. Kim, A.B. et al. JCI Insight. Mar 2024.
TEM of Human Synthetic Amyloid Beta 1-42 Oligomers (catalog# SPR-488).
- Catalog# SPR-485: Human Synthetic Amyloid Beta 1-42 Peptide (HFIP-treated)
- Catalog# SPR-488: Human Synthetic Amyloid Beta 1-42 Oligomers
- Catalog# SPR-492: Human Amyloid Beta Pyroglutamate 3-42 Pre-formed Fibrils
- α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity. Horvath, J.D. et al. Cell Rep. Oct 2023.
- Catalog# SPR-487: Human Synthetic Amyloid Beta 1-42 Pre-formed Fibrils