Products

  • Tau-441 (2N4R) P301S Mutant Monomers

    Human Recombinant Tau-441 (2N4R) P301S Mutant Monomers

    Catalog No. SPR-327

    5.00 out of 5 based on 1 customer rating
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    Expression System E. coli
    Tags No tag
    SKU: SPR-327 Category:

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    SPR-327_Tau-Protein-Monomer-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in active tau monomers (SPR-327). A greater increase in fluorescence is seen when 50 μM active monomer (SPR-327) is combined with 10 μM of active fibrils (SPR-329 or SPR-330), as the active fibrils seed the formation of new fibrils from the pool of active monomers.

  • HOP Protein

    Human Recombinant HOP Protein

    Catalog No. SPR-302

    5.00 out of 5 based on 1 customer rating
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    Expression System E. coli
    Tags His tag
    SKU: SPR-302 Category:

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    SPR-302_HOP_Protein_SDS-Page.png

  • Alpha Synuclein Pre-formed Fibrils

    Human Recombinant Alpha Synuclein PFFs (Type 1)

    Catalog No. SPR-322

    5.00 out of 5 based on 1 customer rating
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    Expression System E. coli
    Tags No tag
    SKU: SPR-322 Category:

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    SPR-322_Alpha-Synuclein-Protein-Preformed-Fibrils-Protein-TEM-7.png
    Αlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.ICC/IF of human Alpha Synuclein Protein Preformed Fibrils Protein (SPR-322)ICC/IF of human Alpha Synuclein Protein Preformed Fibrils Protein (SPR-322)StressMarq’s Alpha Synuclein PFFs (red) cat#SPR-322, were shown to be taken up by SH-SY5Y cells and transmitted to neuronal iPSCs within 14 days.SDS-Page of Type 1 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-322)Type 1 alpha synuclein Pre-formed fibrils (SPR-322) seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) as shown by increased fluorescence intensity by Thioflavin T over time.Immunocytochemistry/Immunofluorescence of Human Alpha Synuclein Protein Protein (SPR-322)Mouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFsMouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFs cause endogenous alpha synuclein phosphorylationTEM of Type 1 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-322)IHC of Sprague-Dawley rat brain injected with Type 1 human alpha synuclein Pre-formed fibrils (SPR-322)Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).

  • Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils: ATTO 488

    Human Recombinant Tau-441 (2N4R) P301S Mutant PFFs: ATTO 488

    Catalog No. SPR-329-A488

    5.00 out of 5 based on 1 customer rating
    Reviews (1)
    Expression System E. coli
    Tags ATTO 488
    SKU: SPR-329-A488 Category:

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    SPR-329-A488_Tau-Protein-Protein-TEM-1.png
    TEM of ATTO conjugated tau pre-formed fibrilsThioflavin T assay of ATTO-488 conjugated tau fibrils

  • Anti-ENaC beta Antibody

    Rabbit Anti-Rat ENaC beta Polyclonal

    Catalog No. SPC-404

    4.00 out of 5 based on 3 customer ratings
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    Species Reactivity Hu, Ms, Rt, Xe, Hm
    Applications WB IHC ICC/IF FCM IP
    SKU: SPC-404 Categories: ,

    SPC-404_ENaC_Antibody_IHC_Rat_kidney-tissue_1.png
    Rabbit Anti-ENaC Antibody used in Western blot (WB) on kidney tissue lysates (SPC-404)Rabbit Anti-ENaC Antibody used in Western blot (WB) on mpkCCD cell lysates (SPC-404)Rabbit Anti-ENaC Antibody used in Western blot (WB) on kidney cortex (SPC-404)

  • Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils

    Human Recombinant Tau-441 (2N4R) P301S Mutant PFFs

    Catalog No. SPR-329

    5.00 out of 5 based on 1 customer rating
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    Expression System E. coli
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    SKU: SPR-329 Category:

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    SPR-329_Tau-Protein-Peformed-Fibrils-TEM-1.png
    TEM of recombinant Tau441 (2N4R), P301S mutant Pre-formed Fibrils (PFFs)Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) when tau Pre-formed fibrils (SPR-329) are combined with tau monomers (SPR-327). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.SDS-PAGE of ~67 kDa Human Tau 2N4R P301S Pre-formed Fibrils (PFFs)

  • Urolithin A

    Mitophagy inducer

    Catalog No. SIH-610

    0 out of 5 based on 0 customer ratings
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    CAS No. 1143-70-0
    Molecular Formula C13H8O4
    SKU: SIH-610 Categories: ,

    SIH-610-Urolithin-A-Chemical-Structure.png

  • MS-275

    HDAC inhibitor

    Catalog No. SIH-416

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    CAS No. 209783-80-2
    Molecular Formula C21H20N4O3
    SKU: SIH-416 Categories: ,

    SIH-416_MS_275_Chemical_Structure.png