AAL 993

Name: AAL 993
SKU: SIH-424
Availability: InStock

VEGFR inhibitor

Catalog No. SIH-424

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CAS No.	269390-77-4
Molecular Formula	C20H16F3N3O

SKU: SIH-424 Categories: Inhibitor, Small Molecules

Product Name	AAL 993
Description	VEGFR inhibitor
Purity	>98% (TLC)
CAS No.	269390-77-4
Molecular Formula	C₂₀H₁₆F₃N₃O
Molecular Weight	371.4
Field of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Storage Temperature	-20ºC
Shipping Temperature	Shipped Ambient
Product Type	Inhibitor
Solubility	Soluble in DMSO (>25 mg/ml) or ethanol (15 mg/ml)
Source	Synthetic
Appearance	Pale yellow solid
SMILES	C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NCC3=CC=NC=C3
InChI	InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
InChIKey	BLAFVGLBBOPRLP-UHFFFAOYSA-N
Safety Phrases	Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product	AAL 993 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-424)

Alternative Names	2-[(4-Pyridyl)methyl]amino-N-[3-(trifluoromethyl)phenyl]benzamide
Research Areas	Apoptosis, Cancer, Cancer Growth Inhibitors, Cardiovascular System, Cell Signaling, Growth Factor Receptor Inhibitors
PubChem ID	6398883
Scientific Background	AAL-993 is a very potent inhibitor of VEGFR-1, VEGFR-2 and VEGFR-3, as well as PDGFR-β, c-Kit and CSF-1R at higher concentrations.
References	1. Manley P.W., et al. (2004) Biochimica Biophysica Acta. 1697(1-2): 17–27. 2. Ban H.S., Uno M., & Nakamura H. (2010) Cancer Letters. 296(1): 17–26.

Chemical structure of AAL 993 (SIH-424), a VEGFR inhibitor. CAS #: N/A. Molecular Formula: C20H16F3N3O. Molecular Weight: 371.4 g/mol.

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