AG1296

PDGFR kinase inhibitor

Catalog No. SIH-426

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CAS No. 146535-11-7
Molecular Formula C16H14N2O2
SKU: SIH-426 Categories: ,

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SIH-426_AG-1296_Chemical_Structure.png
Product Name AG1296
Description

PDGFR kinase inhibitor

Purity >98% (TLC)
CAS No. 146535-11-7
Molecular Formula C16H14N2O2
Molecular Weight 266.3
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble in DMSO or dichloromethane
Source Synthetic
Appearance Off-white to brownish solid
SMILES C1=C(OC)C(=CC2=NC=C(N=C12)C3=CC=CC=C3)OC
InChI InChI=1S/C16H14N2O2/c1-19-15-8-12-13(9-16(15)20-2)18-14(10-17-12)11-6-4-3-5-7-11/h3-10H,1-2H3
InChIKey QNOXYUNHIGOWNY-UHFFFAOYSA-N
Safety Phrases Classification:
Not a hazardous substance or mixture.

Safety Phrases:
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product AG1296 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-426)

Biological Description

Alternative Names Tyrphostin AG 1296, 6,7-Dimethoxy-3-phenylquinoxaline, 6,7-Dimethoxy-2-phenylquinoxaline
Research Areas Apoptosis, Cancer, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID 2049
Scientific Background AG-1296 is a potent and specific inhibitor of PDGF receptor tyrosine kinase. AG-1296 is cell-permeable.
References 1. Strutz F., et al. (2001) Kidney Int. 59(2): 579–592.

Product Images

<p>Chemical structure of AG1296 (SIH-426), a PDGFR kinase inhibitor. CAS #: 146535-11-7. Molecular Formula: C16H14N2O2. Molecular Weight: 266.3 g/mol.</p>

Chemical structure of AG1296 (SIH-426), a PDGFR kinase inhibitor. CAS #: 146535-11-7. Molecular Formula: C16H14N2O2. Molecular Weight: 266.3 g/mol.

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