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| Product Name | Formoterol hemifumarate |
| Description |
Beta2 adrenoceptor agonist |
| Purity | ≥99% (HPLC); NMR (Conforms) |
| CAS No. | 43229-80-7 |
| Molecular Formula | C19H24N2O4 • ½ C4H4O4 |
| Molecular Weight | 402.5 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Agonist |
| Solubility | May be dissolved in DMSO (20 mg/ml) |
| Source | Synthetic |
| Appearance | White to Off-White Powder |
| SMILES | CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O.CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O.C(=CC(=O)O)C(=O)O |
| InChI | InChI=1S/2C19H24N2O4.C4H4O4/c2*1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22;5-3(6)1-2-4(7)8/h2*3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22);1-2H,(H,5,6)(H,7,8)/b;;2-1+/ |
| InChIKey | OBRNDARFFFHCGE-PERKLWIXSA-N |
| Safety Phrases | Not a hazardous substance or mixture. |
| Cite This Product | Formoterol hemifumarate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-593) |
Biological Description
| Alternative Names | (R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide; BD 40A |
| Research Areas | Neuroscience, Neurotransmission, Neurotransmitter Receptors |
| PubChem ID | 9832292 |
| Scientific Background | Formoterol hemifumarate is a long-acting β2-adrenergic receptor agonist commonly used as a bronchodilator in respiratory diseases. It stimulates intracellular adenyl cyclase, increasing cyclic AMP (cAMP) levels and promoting smooth muscle relaxation. In neurodegenerative disease research, β2-adrenergic agonists like Formoterol are being explored for their neuroprotective and anti-inflammatory effects. Elevated cAMP signaling has been associated with enhanced neuronal survival, reduced microglial activation, and improved cognitive function, suggesting potential therapeutic relevance in conditions such as Alzheimer’s disease. |
| References | https://pubchem.ncbi.nlm.nih.gov/compound/Formoterol-hemifumarate |
Product Images
Chemical structure of Formoterol hemifumarate (SIH-593), a Beta2 adrenoceptor agonist. CAS #: . Molecular Formula: C19H24N2O4 • ½ C4H4O4. Molecular Weight: 402.5 g/mol.
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