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| Product Name | Allopregnanolone |
| Description |
Positive allosteric modulator of GABAA receptors |
| Purity | >98% (HPLC); NMR (conforms) |
| CAS No. | 516-54-1 |
| Molecular Formula | C21H34O2 |
| Molecular Weight | 318.5 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (32 mg/ml); or Ethanol (32 mg/ml) |
| Source | Synthetic |
| Appearance | White to off-white powder |
| SMILES | CC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C |
| InChI | InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15+,16-,17+,18-,19-,20-,21+/m0/s1 |
| InChIKey | AURFZBICLPNKBZ-SYBPFIFISA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | Allopregnanolone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-582) |
Biological Description
| Alternative Names | (3α,5α)-3-Hydroxy-pregnan-20-one; (3α,5α)-tetrahydroprogesterone; 3-OH-DHP |
| Research Areas | Cell Signaling, Neuroscience |
| PubChem ID | 92786 |
| Scientific Background | Allopprenanolone is a natural metabolite of progesterone that is devoid of any progestational activity. It acts and functions as a potent ligand of GABA type A receptor complexes in the CNS. It is a neuroactive steroid. Has recently been approved as a drug for postpartum depression by the FDA. |
Product Images
Chemical structure of Allopregnanolone (SIH-582), a Positive allosteric modulator of GABAA receptors
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