Discovery through Partnership | Excellence through Quality
| Product Name | Nalmefene HCl |
| Description |
Opioid Receptor Antagonist |
| Purity | >98% (HPLC); NMR (conforms) |
| CAS No. | 58895-64-0 |
| Molecular Formula | C21H25NO3 • HCl |
| Molecular Weight | 375.9 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Antagonist |
| Solubility | May be dissolved in water (25 mg/ml) |
| Source | Synthetic |
| Appearance | White powder |
| SMILES | C=C1CCC2(C3CC4=C5C2(C1OC5=C(C=C4)O)CCN3CC6CC6)O.Cl |
| InChI | InChI=1S/C21H25NO3.ClH/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13;/h4-5,13,16,19,23-24H,1-3,6-11H2;1H/t16-,19+,20+,21-;/m1./s1 |
| InChIKey | GYWMRGWFQPSQLK-OPHZJPRHSA-N |
| Safety Phrases |
Classification: Danger. Hazard Statements: H301 - H336 - H410 Precautionary Statements: P261 - P264 - P270 - P271 - P273 - P301 + P310 |
| Cite This Product | Nalmefene HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-621) |
Biological Description
| Alternative Names | (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylene-morphinan-3,14-diol, hydrochloride |
| PubChem ID | 5388881 |
| Scientific Background | Nalmefene HCl is an opioid receptor antagonist with a longer duration of action compared to Naloxone. It is primarily used in the treatment of alcohol dependence and has been studied for its ability to block the effects of various opioid receptor agonists. In neuroscience, Nalmefene is relevant for exploring the role of opioid signaling in addiction, reward pathways, and neurobehavioral disorders. |
| References |
1.Osborn, M.D., et al. (201) Life Sci. 86:624. 2. Butelman E.R., et al. (2009) J. Pharmacol. Exp. Ther. 328:588. 3.Butelman E.R., et al. (2008) J. Pharmacol. Exp. Ther. 327:154. 4.Soyka M., and Rosner S. (2008) Curr. Drug Abuse Rev. 1:280. |
Product Images
Powered by Bioz
Reviews
There are no reviews yet.