Discovery through Partnership | Excellence through Quality
| Product Name | Ambroxol HCl |
| Description |
Free radical scavenger |
| Purity | >98% |
| CAS No. | 23828-92-4 |
| Molecular Formula | C13H18Br2N2O•HCl |
| Molecular Weight | 414.57 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Antioxidant |
| Solubility | Soluble to 50 mM in DMSO |
| Source | Synthetic |
| Appearance | White Solid |
| SMILES | C1CC(CCC1NCC2=C(C(=CC(=C2)Br)Br)N)O |
| InChI | InChI=1S/C13H18Br2N2O/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10/h5-6,10-11,17-18H,1-4,7,16H2 |
| InChIKey | JBDGDEWWOUBZPM-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Hazard Phrases: H302 |
| Cite This Product | Ambroxol HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-153) |
Biological Description
| Alternative Names | 4-[(2-Amino-3,5-dibromobenzyl)amino]cyclohexanol |
| Research Areas | Cancer, Oxidative Stress |
| PubChem ID | 2132 |
| Scientific Background | Ambroxol HCl is a mucolytic agent with potent sodium channel-blocking activity and notable antioxidant and anti-inflammatory properties. In neuroscience, ambroxol has gained attention for its ability to enhance lysosomal function and promote the clearance of misfolded proteins, particularly glucocerebrosidase in Parkinson’s disease models. Its neuroprotective effects are attributed to improved autophagy, reduced neuroinflammation, and stabilization of neuronal ion channels. These mechanisms support its potential as a disease-modifying therapy in neurodegenerative disorders. |
| References |
1. Weiser T. (2006) Neurosci Lett. 395: 179-184. 2. Sanderson R.J., et al. (1976) Respir Phys. 27: 379-392. |
Product Images
Chemical structure of Ambroxol HCl (SIH-153), a Free radical scavenger. CAS #: 23828-92-4. Molecular Formula: C13H18Br2N2O * HCl. Molecular Weight: 414.57 g/mol.
Powered by Bioz
Reviews
There are no reviews yet.