Ambroxol HCl

Free radical scavenger

Catalog No. SIH-153

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CAS No. 23828-92-4
Molecular Formula C13H18Br2N2O•HCl
SKU: SIH-153 Categories: ,

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SIH-153_Ambroxol_HCl_Chemical_Structure.png
Product Name Ambroxol HCl
Description

Free radical scavenger

Purity >98%
CAS No. 23828-92-4
Molecular Formula C13H18Br2N2O•HCl
Molecular Weight 414.57
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Antioxidant
Solubility Soluble to 50 mM in DMSO
Source Synthetic
Appearance White Solid
SMILES C1CC(CCC1NCC2=C(C(=CC(=C2)Br)Br)N)O
InChI InChI=1S/C13H18Br2N2O/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10/h5-6,10-11,17-18H,1-4,7,16H2
InChIKey JBDGDEWWOUBZPM-UHFFFAOYSA-N
Safety Phrases Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Hazard Phrases:
H302
Cite This Product Ambroxol HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-153)

Biological Description

Alternative Names 4-[(2-Amino-3,5-dibromobenzyl)amino]cyclohexanol
Research Areas Cancer, Oxidative Stress
PubChem ID 2132
Scientific Background Ambroxol HCl is a mucolytic agent with potent sodium channel-blocking activity and notable antioxidant and anti-inflammatory properties. In neuroscience, ambroxol has gained attention for its ability to enhance lysosomal function and promote the clearance of misfolded proteins, particularly glucocerebrosidase in Parkinson’s disease models. Its neuroprotective effects are attributed to improved autophagy, reduced neuroinflammation, and stabilization of neuronal ion channels. These mechanisms support its potential as a disease-modifying therapy in neurodegenerative disorders.
References 1. Weiser T. (2006) Neurosci Lett. 395: 179-184.
2. Sanderson R.J., et al. (1976) Respir Phys. 27: 379-392.

Product Images

<p>Chemical structure of Ambroxol HCl (SIH-153), a Free radical scavenger. CAS #: 23828-92-4. Molecular Formula: C13H18Br2N2O * HCl. Molecular Weight: 414.57 g/mol.</p>

Chemical structure of Ambroxol HCl (SIH-153), a Free radical scavenger. CAS #: 23828-92-4. Molecular Formula: C13H18Br2N2O * HCl. Molecular Weight: 414.57 g/mol.

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