BCTC

Name: BCTC
SKU: SIH-307
Availability: InStock

TRPV1 blocker

Catalog No. SIH-307

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CAS No.	393514-24-4
Molecular Formula	C20H25ClN4O

SKU: SIH-307 Categories: Inhibitor, Small Molecules

Product Name	BCTC
Description	TRPV1 blocker
Purity	>98%
CAS No.	393514-24-4
Molecular Formula	C₂₀H₂₅ClN₄O
Molecular Weight	372.89
Field of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Storage Temperature	-20ºC
Shipping Temperature	Shipped Ambient
Product Type	Inhibitor
Solubility	Soluble to 100 mM in DMSO and to 40 mM in ethanol
Source	Synthetic
Appearance	White Solid
SMILES	CC(C)(C)C1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=C(C=CC=N3)Cl
InChI	InChI=1S/C20H25ClN4O/c1-20(2,3)15-6-8-16(9-7-15)23-19(26)25-13-11-24(12-14-25)18-17(21)5-4-10-22-18/h4-10H,11-14H2,1-3H3,(H,23,26)
InChIKey	ROGUAPYLUCHQGK-UHFFFAOYSA-N
Safety Phrases	Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Cite This Product	BCTC (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-307)

Alternative Names	4-(3-Chloro-2-pyridinyl)-N-[4-(2-methyl-2-propanyl)phenyl]-1-piperazinecarboxamide
Research Areas	Ion Channels, Neuroscience
PubChem ID	9929425
Scientific Background	BCTC is an inhibitor of capsaicin- and acid-mediated currents at rat VR1. Thus it has effects on acute, inflammatory and neuropathic pain in rats (1, 2).
References	1. Pomonis J.D., et al. (2003) J Pharmacol Exp Ther. 306(1): 387-393. 2. Valenzano K.J., et al. (2003) J Pharmacol Exp. Ther. 306(1): 377-386.

Chemical structure of BCTC (SIH-307), a TRPV1 blocker. CAS #: 393514-24-4. Molecular Formula: C20H25ClN4O. Molecular Weight: 372.89 g/mol.

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