BML 259

CDK5, p25 kinase inhibitor

Catalog No. SIH-435

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CAS No. 267654-00-2
Molecular Formula C14H16N2OS
SKU: SIH-435 Categories: ,

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SIH-435_BML-259_Chemical_Structure.png
Product Name BML 259
Description

CDK5, p25 kinase inhibitor

Purity >98% (TLC)
CAS No. 267654-00-2
Molecular Formula C14H16N2OS
Molecular Weight 260.4
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble in DMSO (30 mg/ml), dimethyl formamide (30 mg/ml) or 100% ethanol (0.25 mg/ml)
Source Synthetic
Appearance White solid
SMILES CC(C)C1=CN=C(S1)NC(=O)CC2=CC=CC=C2
InChI InChI=1S/C14H16N2OS/c1-10(2)12-9-15-14(18-12)16-13(17)8-11-6-4-3-5-7-11/h3-7,9-10H,8H2,1-2H3,(H,15,16,17)
InChIKey IGRZXNLKVUEFDM-UHFFFAOYSA-N
Safety Phrases Classification:
Not a hazardous substance or mixture.

Safety Phrases:
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product Bml 259 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-435)

Biological Description

Alternative Names N-(5-Isopropylthiazol-2-yl)phenylacetamide
Research Areas Apoptosis, Cancer, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID 16760027
Scientific Background Bml 259 is a potent inhibitor of Cdk5/p25. It also inhibits Cdk2/cyclin E.
References 1. Kaźmierczak A., Czapski G.A., Adamczyk A., Gajkowska B., & Strosznajder J.B. (2011) Neurochem. Int. 58(2): 206–214.

Product Images

<p>Chemical structure of BML 259 (SIH-435), a CDK5/p25 kinase inhibitor. CAS #: 267654-00-2. Molecular Formula: C14H16N2OS. Molecular Weight: 260.4 g/mol.</p>

Chemical structure of BML 259 (SIH-435), a CDK5/p25 kinase inhibitor. CAS #: 267654-00-2. Molecular Formula: C14H16N2OS. Molecular Weight: 260.4 g/mol.

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