Discovery through Partnership | Excellence through Quality
| Product Name | Cantharidin |
| Description |
Phosphatase PP2A inhibitor |
| Purity | >98% (GC) |
| CAS No. | 56-25-7 |
| Molecular Formula | C10H12O4 |
| Molecular Weight | 196.2 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO or 100% ethanol |
| Source | Synthetic |
| Appearance | White to off-white solid |
| SMILES | C[C@@]12[C@H]3CC[C@@H]([C@@]1(C(=O)OC2=O)C)O3 |
| InChI | InChI=1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3 |
| InChIKey | DHZBEENLJMYSHQ-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Acute toxicity, Oral (Category 2), H300 Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity -single exposure (Category 3), Respiratory system, H335 Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H300 Fatal if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary statements: P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. P321 Specific treatment (see supplemental first aid instructions on this label). P330 Rinse mouth. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ containerto an approved waste disposal plant. |
| Cite This Product | Cantharidin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-519) |
Biological Description
| Alternative Names | 3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione, 7a-Dimethylhexahydro-3a,4,7-epoxyisobenzofuran, Cantharidine, Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzo-furan-1,3-dione |
| Research Areas | Cell Signaling |
| PubChem ID | 2545 |
| Scientific Background | Cantharidin is an inhibitor of protein phosphatase 1 (PP1) and 2A (PP2A). It is a naturally occurring toxin found in Mylabris phalerata. |
| References |
1. Honkanen R. E. (1993) FEBS Letters. 330(3): 283–286. 2. Eldridge R., & Casida J.E. (1995) Toxic. App. Pharm. 130(1): 95–100. |
Product Images
Chemical structure of Cantharidin (SIH-519), a Phosphatase PP2A inhibitor. CAS #: 56-25-7. Molecular Formula: C10H12O4. Molecular Weight: 196.2 g/mol.
Powered by Bioz
Reviews
There are no reviews yet.