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| Product Name | Castanospermine |
| Description |
Glycosidase inhibitor |
| Purity | >99% (TLC), NMR conforms |
| CAS No. | 79831-76-8 |
| Molecular Formula | C8H15NO4 |
| Molecular Weight | 189.2 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in water (25 mg/ml) |
| Source | Synthetic |
| Appearance | Off white powder |
| SMILES | C1CN2C[C@@H]([C@H]([C@@H]([C@H]2[C@H]1O)O)O)O |
| InChI | InChI=1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s2, InChI=1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s3 |
| InChIKey | JDVVGAQPNNXQDW-TVNFTVLESA-N |
| Safety Phrases |
Classification Not WHMIS controlled. Hazard statement(s): H302 + H312 Harmful if swallowed or in contact with skin H332 Harmful if inhaled. Precautionary statement(s): P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ protective clothing. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. P322 Specific measures (see supplemental first aid instructions on this label). P330 Rinse mouth. P363 Wash contaminated clothing before reuse. P501 Dispose of contents/ container to an approved waste disposal plant. |
| Cite This Product | Castanospermine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-529) |
Biological Description
| Alternative Names | 6,7-Diepicastanospermine, 6-Epicastanospermine, 1,6,7,8-Tetrahydroxyoctahydroindolizine, NSC 625381, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidine, (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol |
| Research Areas | Cell Signaling |
| PubChem ID | 54445 |
| Scientific Background | Castanospermine is a potent inhibitor of α- and β-glucosidases, enzymes involved in glycoprotein processing. While primarily studied for its antiviral and anticancer properties, Castanospermine has gained attention in neuroscience for its potential to modulate glycosphingolipid metabolism and reduce neuroinflammation. By interfering with glycoprotein maturation, it may influence protein aggregation and lysosomal function—key factors in neurodegenerative diseases such as Gaucher and Parkinson’s. Its ability to cross the blood-brain barrier and alter glycan processing makes it a valuable tool in neurodegenerative disease models. |
Product Images
Chemical structure of Castanospermine (SIH-529), a Glycosidase inhibitor. CAS #: 79831-76-8. Molecular Formula: C8H15NO4. Molecular Weight: 189.2 g/mol.
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