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| Product Name | CCT241161 |
| Description |
RAF Inhibitor |
| Purity | >98% |
| CAS No. | 1163719-91-2 |
| Molecular Formula | C28H27N7O3S |
| Molecular Weight | 541.63 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Blue Ice or 4ºC |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO |
| Source | Synthetic |
| Appearance | White Solid |
| SMILES | CC(C)(C)C1=NN(C2=CC=CC=C2)C(NC(NC(C(SC)=C3)=CC=C3OC4=C5C(NC(C=N5)=O)=NC=C4)=O)=C1 |
| Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | CCT241161 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-186) |
Biological Description
| Alternative Names | 1-(3-(tert-butyl)-1-phenyl-1H-pyrazol-5-yl)-3-(2-(methylthio)-4-((3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy)phenyl)urea |
| Research Areas | Apoptosis, Cancer |
| Scientific Background | CCT241161 is a pan-RAF/SFK inhibitor targeting BRAF and SRC kinases with high potency. Though its primary application is in oncology, its relevance to neuroscience stems from SRC kinase inhibition, which affects neuronal signaling and plasticity. SRC family kinases are implicated in neurodegenerative and neuropsychiatric disorders. By modulating these kinases, CCT241161 may contribute to the development of targeted therapies for CNS diseases involving kinase dysregulation and synaptic dysfunction. |
| References | 1. Girotti, M.R., et al. (2015) Cancer Cell 27.1: 85-96. |
Product Images
Chemical structure of CCT241161 (SIH-186), a RAF Inhibitor. CAS #: 1163719-91-2. Molecular Formula: C28H27N7O3S. Molecular Weight: 541.63 g/mol.
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