Discovery through Partnership | Excellence through Quality
| Product Name | CZC 54252 Hydrochloride |
| Description |
LRRK2 inhibitor |
| Purity | >98% |
| CAS No. | 1191911-27-9, 1330003-04-7 |
| Molecular Formula | C22H26Cl2N6O4S |
| Molecular Weight | 541.5 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble to 100 mM in DMSO |
| Source | Synthetic |
| Appearance | Yellow solid |
| SMILES | COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl.Cl |
| InChI | InChI=1S/C22H25ClN6O4S.ClH/c1-32-20-13-15(29-9-11-33-12-10-29)7-8-19(20)26-22-24-14-16(23)21(27-22)25-17-5-3-4-6-18(17)28-34(2,30)31;/h3-8,13-14,28H,9-12H2,1-2H3,(H2,24,25,26,27);1H |
| InChIKey | KWCBHUPLQMUKAF-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | CZC 54252 Hydrochloride (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-439) |
Biological Description
| Alternative Names | N-{2-[(5-Chloro-2-{[2-methoxy-4-(4-morpholinyl)phenyl]amino}-4-pyrimidinyl)amino]phenyl}methanesulfonamide hydrochloride |
| Research Areas | Cell Signaling, Neurodegeneration, Neuroscience, Multiple System Atrophy |
| Scientific Background | CZC 54252 Hydrochloride is a potent leucine-rich repeat kinase 2 (LRRK2) inhibitor. |
| References | 1. Kramer T., Lo Monte F., Göring S., Okala Amombo G.M., & Schmidt B. (2012) ACS Chem. Neuro. 3(3): 151–160. |
Product Images
Chemical structure of CZC 54252 Hydrochloride (SIH-439), a LRRK2 inhibitor. CAS #: 1191911-27-9. Molecular Formula: C22H26Cl2N6O4S. Molecular Weight: 541.5 g/mol.
Powered by Bioz
Reviews
There are no reviews yet.