D-AP5.Na

NMDA receptor antagonist

Catalog No. SIH-412

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CAS No. 14375-45-2
Molecular Formula C5H12NO5P.Na
SKU: SIH-412 Categories: ,

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SIH-412_DAP5-NA_Chemical_Structure.png
Product Name D-AP5.Na
Description

NMDA receptor antagonist

Purity >99.5
CAS No. 14375-45-2
Molecular Formula C5H12NO5P.Na
Molecular Weight 219.11
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Antagonist
Solubility Soluble in 1 M NH4OH (50 mg/ml); water (9 mg/ml).
Source Synthetic
Appearance White solid
SMILES [C@@H]([NH3+])(CCC[P]([O-])([O-])=O)C([O-])=O
Safety Phrases Classification: Not WHMIS controlled.
Safety Phrases:
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product D-AP5.Na (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-412)

Biological Description

Alternative Names D-amino-5-phosphonopentaoic acid sodium salt
Research Areas Glutamate Receptors, Ion Channels, Neuroscience, Neurotransmitter Receptors, NMDA Receptors
Scientific Background DAP5 is used widely as a potent and selective NMDA receptor antagonist. It represents the active enantiomer form of AP5 (2-amino-5-phosphonopentanoic acid).
References 1. Davies J., & Watkins J. (1982) Brain Res. 378-86.
2. Schulte M., Roon R., Chalmers D., Sunter D., & Koerner J. (1994) Brain Res. 203-7.

Product Images

<p>Chemical structure of D-AP5.Na (SIH-412), a Glutamate-NMDA receptor antagonist. CAS #: 14375-45-2. Molecular Formula: C5H12NO5P.Na. Molecular Weight: 219.11 g/mol.</p>

Chemical structure of D-AP5.Na (SIH-412), a Glutamate-NMDA receptor antagonist. CAS #: 14375-45-2. Molecular Formula: C5H12NO5P.Na. Molecular Weight: 219.11 g/mol.

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