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| Product Name | Diazoxide |
| Description |
K-ATP channel activator |
| Purity | >98% (HPLC); NMR (conforms) |
| CAS No. | 364-98-7 |
| Molecular Formula | C8H7ClN2O2S |
| Molecular Weight | 230.7 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Blue Ice or 4ºC |
| Product Type | Activator |
| Solubility | May be dissolved in DMSO (20 mg/ml) |
| Source | Synthetic |
| Appearance | White powder |
| SMILES | CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl |
| InChI | InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11) |
| InChIKey | GDLBFKVLRPITMI-UHFFFAOYSA-N |
| Safety Phrases |
WHMIS Classification: D2B Toxic Material Causing Other Toxic - Effects Moderate skin irritant, Moderate respiratory irritant, Moderate eye irritant GHS Classification: Acute toxicity, Oral (Category 4) Skin irritation (Category 2) Eye irritation (Category 2A) Specific target organ toxicity - single exposure (Category 3) Signal word: Warning Hazard statement(s): H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary statement(s): P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. P321 Specific treatment (see supplemental first aid instructions on this label). P330 Rinse mouth. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant. |
| Cite This Product | Diazoxide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-548) |
Biological Description
| Alternative Names | 7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide |
| Research Areas | Ion Channels, Neuroscience, Potassium Channels |
| PubChem ID | 3019 |
| Scientific Background | Diazoxide is a mitochondrial ATP-sensitive potassium (KATP) channel opener known for its cytoprotective and neuroprotective effects. In neuroscience, it has been shown to reduce neuronal apoptosis, oxidative stress, and excitotoxicity in models of stroke and neurodegeneration. By modulating mitochondrial function and preserving cellular energy balance, Diazoxide offers therapeutic potential in conditions such as Alzheimer’s disease, Parkinson’s disease, and ischemic brain injury. |
Product Images
Chemical structure of Diazoxide (SIH-548), a K-ATP channel activator. CAS #: 364-98-7. Molecular Formula: C8H7ClN2O2S. Molecular Weight: 230.7 g/mol.
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