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| Product Name | CPD5 (Discontinued) |
| Description |
MPS1/TTK Inhibitor |
| Purity | 99.1% |
| Molecular Formula | C33H40N8O2 |
| Molecular Weight | 580.74 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Blue Ice or 4ºC |
| Product Type | Inhibitor |
| Solubility | Soluble in CDCI3 |
| Source | Synthetic |
| Appearance | Yellow Solid |
| SMILES | COC1=CC(N2CCN(C)CC2)=CC=C1N C3=NC=C(CCC4=C5N(C)N=C4C(NC 6=C(CC)C=CC=C6CC)=O)C5=N3 |
| InChI | InChI=1S/C12H19N3O/c1-14-5-7-15(8-6-14)10-3-4-11(13)12(9-10)16-2/h3-4,9H,5-8,13H2,1-2H3 |
| InChIKey | LUYPGLRYFIVYTH-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | CPD5 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-183) |
Biological Description
| Alternative Names | N-(2,6-diethylphenyl)-8-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide |
| Research Areas | Cancer, Cell Signaling |
| Scientific Background | This is a protein kinase inhibitor with activity against MPS1/TTK. It has an IC50 of 0.10 µM in cellular proliferation inhibition assay using A2780 cells. |
| References | 1. Caldarelli, M., et al. (2011) Bioorganic & Medicinal Chemistry Letters 21.15: 4507-4511. |
Product Images
Chemical structure of CPD5 (SIH-183), a MPS1/TTK Inhibitor. CAS #: . Molecular Formula: C33H40N8O2. Molecular Weight: 580.74 g/mol.
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