Fluoxetine HCl

Serotonin reuptake inhibitor

Catalog No. SIH-631

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CAS No. 56296-78-7
Molecular Formula C17H18F3NO • HCl
SKU: SIH-631 Categories: ,

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SIH-631-Fluoxetine-HCl-Chemical-Structure.png
Product Name Fluoxetine HCl
Description

Serotonin reuptake inhibitor

Purity ≥98% (HPLC); NMR (Conforms)
CAS No. 56296-78-7
Molecular Formula C17H18F3NO • HCl
Molecular Weight 345.8
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility May be dissolved in DMSO (35 mg/ml); or water (4 mg/ml)
Source Synthetic
Appearance White powder
SMILES CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl
InChI InChI=1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H
InChIKey GIYXAJPCNFJEHY-UHFFFAOYSA-N
Safety Phrases Classification: Danger
GHS Hazard Statements,
H302 (98%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (92.1%): Causes skin irritation [Warning Skin corrosion/irritation]
H318 (96%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
H400 (58.4%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

Precautionary Statement Codes,: P264, P264+P265, P270, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P332+P317, P362+P364, P391, and P501
Cite This Product Fluoxetine HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-631)

Biological Description

Alternative Names (±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride; LY-110,140
Research Areas Neurodegeneration, Neuroscience, Neurotransmission, Stem Cells, Neural Stem Cells
PubChem ID 62857
Scientific Background Fluoxetine HCl is a selective serotonin reuptake inhibitor (SSRI) widely used as an antidepressant. It exhibits high selectivity for the serotonin transporter and has demonstrated neuroprotective and neurogenic effects. Fluoxetine enhances neuronal precursor proliferation and differentiation, reduces neuroinflammation, and improves outcomes in models of brain injury and neurodegeneration. It is also being explored for its potential in autism spectrum disorders and cognitive enhancement.
References 1. M Tatsumi et al. Eur. J. Pharmacol. 1997 340:249
2. P Benfield et al. Drugs 1986 32:481
3. A Benvenuto et al. Brain Dev. 2013 35:119
4. FY Liu et al. J. Neuroinflammation 2018 15:347
5. EA Chang et al. Int. J. Dev. Biol. 2010 54:707

Product Images

<p>Chemical structure of Fluoxetine HCl (SIH-631), a Serotonin reuptake inhibitor. CAS #: 56296-78-7. Molecular Formula: C17H18F3NO  • HCl. Molecular Weight: 345.8 g/mol.</p>

Chemical structure of Fluoxetine HCl (SIH-631), a Serotonin reuptake inhibitor. CAS #: 56296-78-7. Molecular Formula: C17H18F3NO • HCl. Molecular Weight: 345.8 g/mol.

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