Discovery through Partnership | Excellence through Quality
| Product Name | Itraconazole |
| Description |
Cytochrome P450 inhibitor |
| Purity | >98% |
| CAS No. | 84625-61-6 |
| Molecular Formula | C35H38Cl2N8O4 |
| Molecular Weight | 705.6 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in chloroform (50 mg/ml) |
| Source | Synthetic |
| SMILES | CCC(C)N1N=CN(C1=O)c2ccc(cc2)N3CCN(CC3)c4ccc(OC[C@H]5CO[C@@](Cn6cncn6)(O5)c7ccc(Cl)cc7Cl)cc4 |
| InChI | 1S/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,1 |
| InChIKey | VHVPQPYKVGDNFY-ZPGVKDDISA-N |
| Safety Phrases |
Classification: D1B Toxic Material Causing Immediate and Serious Toxic Effects - Toxic by ingestion D2A Very Toxic Material Causing Other Toxic Effects - Teratogen D2B Toxic Material Causing Other Toxic Effects - Moderate skin irritant, Moderate respiratory irritant, Moderate eye irritant Hazard statement(s): H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary statement(s): P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| Cite This Product | Itraconazole (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-543) |
Biological Description
| Alternative Names | Itraconazole, 84625-61-6, Sporanox, ITRAZOLE, Itraconazolum, Oriconazole, R51211, Sporanox, 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one |
| Research Areas | Angiogenesis, Autophagy, Cancer, Cardiovascular System, Growth Factors |
| PubChem ID | 3793 |
| Scientific Background | Itraconazole is an triazol antifungal agent. It inhibits P-450 dependent enzymes, which results in the inhibition of ergosterol synthesis. |
Product Images
Chemical structure of Itraconazole (SIH-543), a Cytochrome P450 inhibitor. CAS #: 84625-61-6. Molecular Formula: C35H38Cl2N8O4. Molecular Weight: 705.6 g/mol.
Powered by Bioz
Reviews
There are no reviews yet.