LYS6K2

Name: LYS6K2
SKU: SIH-462
Availability: InStock

S6 kinase inhibitor

Catalog No. SIH-462

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CAS No.
Molecular Formula	C21H19F4N7

SKU: SIH-462 Categories: Inhibitor, Small Molecules

Product Name	LYS6K2
Description	S6 kinase inhibitor
Purity	97% (HPLC)
Molecular Formula	C₂₁H₁₉F₄N₇
Molecular Weight	445.4
Field of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Storage Temperature	-20ºC
Shipping Temperature	Shipped Ambient
Product Type	Inhibitor
Solubility	Soluble in DMSO (up to 1 mg/ml) or DMF (up to 3 mg/ml with warming)
Source	Synthetic
Appearance	Yellow solid
SMILES	Cn1cc(nc1C2CCN(CC2)c3c4cn[nH]c4ncn3)c5ccc(c(c5)C(F)(F)F)F
InChI	InChI=1S/C21H19F4N7/c1-31-10-17(13-2-3-16(22)15(8-13)21(23,24)25)29-19(31)12-4-6-32(7-5-12)20-14-9-28-30-18(14)26-11-27-20/h2-3,8-12H,4-7H2,1H3,(H,26,27,28,30)
InChIKey	FYXRSVDHGLUMHB-UHFFFAOYSA-N
Safety Phrases	Classification: Skin Category 2 Eye Category 2A Specific target organ toxicity - single exposure (Category 3 Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary statements: P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P280 Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations.
Cite This Product	LYS6K2 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-462)

Alternative Names	4-(4-(4-(4-fluoro-3-(trifluoromethyl) phenyl)-1-methyl-1H-imidazol-2-yl) piperidin-1-yl)-1H-pyrazolo [3,4-d] pyrimidine
Research Areas	Apoptosis, Cancer, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID	25118925
Scientific Background	LYS6K2 is a selective inhibitor of the p70 ribosomal S6 kinase. Specifically, it blocks the phosphorylation of S6. LYS6K2 is cell permeable.
References	1. Fenton T.R., & Gout I.T. (2011) Int. J. Biochem. Cell Biol. 43(1): 47–59.

Chemical structure of LYS6K2 (SIH-462), a S6 kinase inhibitor. CAS #: N/A. Molecular Formula: C21H19F4N7. Molecular Weight: 445.4 g/mol.

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