Product Name | MAPKII Kinase Inhibitor |
Description |
Hsp25 Kinase Inhibitor |
Purity | >95% |
Molecular Formula | C61H113N21O6 |
Molecular Weight | 1396.7 |
Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Storage Temperature | -20ºC |
Shipping Temperature | Shipped Ambient |
Product Type | Inhibitor |
Solubility | Soluble in DMSO or H20 |
Source | Synthetic |
Appearance | White Solid |
Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
Cite This Product | MAPKII Kinase Inhibitor (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-120) |
Research Areas | Cancer, Heat Shock |
Scientific Background | MAPKII Kinase Inhibitor targets MAPKAP kinase II (MK2), a key component of the p38 MAPK pathway involved in cellular stress responses. MK2 is activated by various chemical and biological stressors, including oxidative stress, cytokines, and irradiation. In neurodegenerative disease research, MK2 has emerged as a therapeutic target due to its role in neuroinflammation—a hallmark of conditions such as Alzheimer's and Parkinson's disease. By inhibiting MK2, this compound may attenuate inflammatory signaling cascades and reduce neuronal damage. Its modulation of stress-activated pathways positions it as a promising candidate for intervention in neuroinflammatory and neurodegenerative disorders. |
References |
1. Pearson G. et al. (2001). Endocrine Reviews 22 (2): 153-183. 2. Fan Y., et al. (2007) Mol. Cells 23 (1): 30-38. 3. Deng et al. (2003) Cell 115: 61-70. |
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