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| Product Name | Mifepristone (RU486) |
| Description |
Glucocorticoid antagonist |
| Purity | >98% |
| CAS No. | 84371-65-3 |
| Molecular Formula | C29H35NO2 |
| Molecular Weight | 429.6 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble to 100 mM in DMSO, and to 50 mM in ethanol |
| Source | Synthetic |
| Appearance | Yellow solid |
| SMILES | CC#C[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)O |
| InChI | InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3) |
| InChIKey | VKHAHZOOUSRJNA-GCNJZUOMSA-N |
| Safety Phrases |
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H360 Precautionary Phrases: P201-P308 + P313 |
| Cite This Product | Mifepristone (RU486) (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-211) |
Biological Description
| Alternative Names | (11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one, RU486, RU 38486 |
| Research Areas | Apoptosis, Cancer |
| PubChem ID | 55245 |
| Scientific Background | Mifepristone is a progesterone receptor antagonist with antiglucocorticoid and antiandrogen properties. In neuroscience, it is investigated for its role in modulating stress responses and glucocorticoid signaling. Its high affinity for glucocorticoid receptors positions it as a potential modulator of neuroendocrine and neuroinflammatory pathways. |
| References | 1. Heikinheim O., Kekkonen R. and Lahteenmaki P. (2003) Contraception. 68(6): 421-426. |
Product Images
Chemical structure of Mifepristone (RU486) (SIH-211), a Glucocorticoid antagonist. CAS #: 84371-65-3. Molecular Formula: C29H35NO2 . Molecular Weight: 429.6 g/mol.
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