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| Product Name | Miglitol |
| Description |
alpha-glucosidase inhibitor |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 72432-03-2 |
| Molecular Formula | C8H17NO5 |
| Molecular Weight | 207.2 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Blue Ice or 4ºC |
| Product Type | Inhibitor |
| Solubility | May be dissolved in DMSO (50 mg/ml, warm) or water (60 mg/ml) |
| Source | Synthetic |
| Appearance | White crystalline powder |
| SMILES | C1C(C(C(C(N1CCO)CO)O)O)O |
| InChI | InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1 |
| InChIKey | IBAQFPQHRJAVAV-ULAWRXDQSA-N |
| Safety Phrases |
WHMIS Classification: Not WHMIS controlled. Not a dangerous substance or mixture according to the Globally Harmonised System (GHS). HMIS Classification: Health hazard: 0 Flammability: 0 Physical hazards: 0 Potential Health Effects: Inhalation - May be harmful if inhaled. May cause respiratory tract irritation. Skin - May be harmful if absorbed through skin. May cause skin irritation. Eyes - May cause eye irritation. Ingestion - May be harmful if swallowed. |
| Cite This Product | Miglitol (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-552) |
Biological Description
| Alternative Names | MIGLITOL, Glyset, Diastabol, Plumarol, Seibule, (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, N-(2-Hydroxyethyl)-1-deoxynojirimycin, BAY-1099, N-hydroxyethyl-1-desoxy-nojirimycin, N-hydroxyethyl-1-desoxynojirimycin |
| Research Areas | Cell Signaling, Energy Transfer Pathways, Metabolism |
| PubChem ID | 441314 |
| Scientific Background | Miglitol is an oral α-glucosidase inhibitor primarily used in the management of type 2 diabetes. Although not widely studied in neurodegeneration, its structural similarity to iminosugars like DNJ suggests potential for modulating glycosphingolipid metabolism. Emerging interest in glycan processing and lysosomal function in neurodegenerative diseases may expand Miglitol’s relevance in neuroscience research. |
Product Images
Chemical structure of Miglitol (SIH-552), a alpha-glucosidase inhibitor. CAS #: 72432-03-2. Molecular Formula: C8H17NO5. Molecular Weight: 207.2 g/mol.
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