Miglitol

alpha-glucosidase inhibitor

Catalog No. SIH-552

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CAS No. 72432-03-2
Molecular Formula C8H17NO5
SKU: SIH-552 Categories: ,

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SIH-552-Miglitol-Chemical-Structure.png
Product Name Miglitol
Description

alpha-glucosidase inhibitor

Purity >98% (TLC); NMR (Conforms)
CAS No. 72432-03-2
Molecular Formula C8H17NO5
Molecular Weight 207.2
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Product Type Inhibitor
Solubility May be dissolved in DMSO (50 mg/ml, warm) or water (60 mg/ml)
Source Synthetic
Appearance White crystalline powder
SMILES C1C(C(C(C(N1CCO)CO)O)O)O
InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1
InChIKey IBAQFPQHRJAVAV-ULAWRXDQSA-N
Safety Phrases WHMIS Classification:
Not WHMIS controlled.
Not a dangerous substance or mixture according to the Globally Harmonised System (GHS).

HMIS Classification:
Health hazard: 0
Flammability: 0
Physical hazards: 0

Potential Health Effects:
Inhalation - May be harmful if inhaled. May cause respiratory tract irritation.
Skin - May be harmful if absorbed through skin. May cause skin irritation.
Eyes - May cause eye irritation.
Ingestion - May be harmful if swallowed.
Cite This Product Miglitol (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-552)

Biological Description

Alternative Names MIGLITOL, Glyset, Diastabol, Plumarol, Seibule, (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, N-(2-Hydroxyethyl)-1-deoxynojirimycin, BAY-1099, N-hydroxyethyl-1-desoxy-nojirimycin, N-hydroxyethyl-1-desoxynojirimycin
Research Areas Cell Signaling, Energy Transfer Pathways, Metabolism
PubChem ID 441314
Scientific Background Miglitol is an oral α-glucosidase inhibitor primarily used in the management of type 2 diabetes. Although not widely studied in neurodegeneration, its structural similarity to iminosugars like DNJ suggests potential for modulating glycosphingolipid metabolism. Emerging interest in glycan processing and lysosomal function in neurodegenerative diseases may expand Miglitol’s relevance in neuroscience research.

Product Images

<p>Chemical structure of Miglitol (SIH-552), a alpha-glucosidase inhibitor. CAS #: 72432-03-2. Molecular Formula: C8H17NO5. Molecular Weight: 207.2 g/mol.</p>

Chemical structure of Miglitol (SIH-552), a alpha-glucosidase inhibitor. CAS #: 72432-03-2. Molecular Formula: C8H17NO5. Molecular Weight: 207.2 g/mol.

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